Histone H1 protects telomeric repeats from H3K27me3 invasion in
Arabidopsis

J 2023

Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis

TEANO, Gianluca, Lorenzo CONCIA, Lea WOLFF, Leopold CARRON, Ivona BIOCANIN et. al.

Základní údaje

Originální název

Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis

Autoři

TEANO, Gianluca, Lorenzo CONCIA, Lea WOLFF, Leopold CARRON, Ivona BIOCANIN, Kateřina ADAMUSOVÁ (203 Česká republika, domácí), Miloslava FOJTOVÁ (203 Česká republika, domácí), Michael BOURGE, Amira KRAMDI, Vincent COLOT, Ueli GROSSNIKLAUS, Chris BOWLER, Celia BAROUX, Alessandra CARBONE, Aline V PROBST, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ (203 Česká republika, domácí), Jiří FAJKUS (203 Česká republika, domácí), Simon AMIARD, Stefan GROB, Clara BOURBOUSSE a Fredy BARNECHE (garant)

Vydání

Cell Reports, Elsevier, 2023, 2211-1247

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10611 Plant sciences, botany

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 8.800 v roce 2022

Kód RIV

RIV/00216224:14740/23:00133328

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.1016/j.celrep.2023.112894

UT WoS

001057847700001

Klíčová slova anglicky

3D chromosome organization; Arabidopsis; chromatin accessibility; CP: Molecular biology; CP: Plants; H3K27me3; linker histone H1; Polycomb; telomere; Telomere Repeat Binding protein; TRB

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 9. 3. 2024 12:09, Mgr. Eva Dubská

Anotace

V originále

While the pivotal role of linker histone H1 in shaping nucleosome organization is well established, its func-tional interplays with chromatin factors along the epigenome are just starting to emerge. Here we show that, in Arabidopsis, as in mammals, H1 occupies Polycomb Repressive Complex 2 (PRC2) target genes where it favors chromatin condensation and H3K27me3 deposition. We further show that, contrasting with its conserved function in PRC2 activation at genes, H1 selectively prevents H3K27me3 accumulation at telo-meres and large pericentromeric interstitial telomeric repeat (ITR) domains by restricting DNA accessibility to Telomere Repeat Binding (TRB) proteins, a group of H1-related Myb factors mediating PRC2 cis recruitment. This study provides a mechanistic framework by which H1 avoids the formation of gigantic H3K27me3-rich domains at telomeric sequences and contributes to safeguard nucleus architecture.

Návaznosti

GX20-01331X, projekt VaV

Název: Biogeneze a evoluce telomerázy u rostlin

Investor: Grantová agentura ČR, Biogenesis and evolution of telomerase in plants

LTC20003, projekt VaV

Název: Dynamics of telomeres and rDNA loci in plant cell nuclei

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Dynamics of telomeres and rDNA loci in plant cell nuclei, INTER-COST

Citovat

TEANO, Gianluca, Lorenzo CONCIA, Lea WOLFF, Leopold CARRON, Ivona BIOCANIN, Kateřina ADAMUSOVÁ, Miloslava FOJTOVÁ, Michael BOURGE, Amira KRAMDI, Vincent COLOT, Ueli GROSSNIKLAUS, Chris BOWLER, Celia BAROUX, Alessandra CARBONE, Aline V PROBST, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ, Jiří FAJKUS, Simon AMIARD, Stefan GROB, Clara BOURBOUSSE a Fredy BARNECHE. Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis. Cell Reports. Elsevier, 2023, roč. 42, č. 8, s. 1-23. ISSN 2211-1247. Dostupné z: https://dx.doi.org/10.1016/j.celrep.2023.112894.

@article{2367721,
   author = {Teano, Gianluca and Concia, Lorenzo and Wolff, Lea and Carron, Leopold and Biocanin, Ivona and Adamusová, Kateřina and Fojtová, Miloslava and Bourge, Michael and Kramdi, Amira and Colot, Vincent and Grossniklaus, Ueli and Bowler, Chris and Baroux, Celia and Carbone, Alessandra and Probst, Aline V and Procházková Schrumpfová, Petra and Fajkus, Jiří and Amiard, Simon and Grob, Stefan and Bourbousse, Clara and Barneche, Fredy},
   article_number = {8},
   doi = {http://dx.doi.org/10.1016/j.celrep.2023.112894},
   keywords = {3D chromosome organization; Arabidopsis; chromatin accessibility; CP: Molecular biology; CP: Plants; H3K27me3; linker histone H1; Polycomb; telomere; Telomere Repeat Binding protein; TRB},
   language = {eng},
   issn = {2211-1247},
   journal = {Cell Reports},
   title = {Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis},
   url = {https://www.sciencedirect.com/science/article/pii/S2211124723009051},
   volume = {42},
   year = {2023}
}

TY  - JOUR
ID  - 2367721
AU  - Teano, Gianluca - Concia, Lorenzo - Wolff, Lea - Carron, Leopold - Biocanin, Ivona - Adamusová, Kateřina - Fojtová, Miloslava - Bourge, Michael - Kramdi, Amira - Colot, Vincent - Grossniklaus, Ueli - Bowler, Chris - Baroux, Celia - Carbone, Alessandra - Probst, Aline V - Procházková Schrumpfová, Petra - Fajkus, Jiří - Amiard, Simon - Grob, Stefan - Bourbousse, Clara - Barneche, Fredy
PY  - 2023
TI  - Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
JF  - Cell Reports
VL  - 42
IS  - 8
SP  - 1-23
EP  - 1-23
PB  - Elsevier
SN  - 22111247
KW  - 3D chromosome organization
KW  - Arabidopsis
KW  - chromatin accessibility
KW  - CP: Molecular biology
KW  - CP: Plants
KW  - H3K27me3
KW  - linker histone H1
KW  - Polycomb
KW  - telomere
KW  - Telomere Repeat Binding protein
KW  - TRB
UR  - https://www.sciencedirect.com/science/article/pii/S2211124723009051
N2  - While the pivotal role of linker histone H1 in shaping nucleosome organization is well established, its func-tional interplays with chromatin factors along the epigenome are just starting to emerge. Here we show that, in Arabidopsis, as in mammals, H1 occupies Polycomb Repressive Complex 2 (PRC2) target genes where it favors chromatin condensation and H3K27me3 deposition. We further show that, contrasting with its conserved function in PRC2 activation at genes, H1 selectively prevents H3K27me3 accumulation at telo-meres and large pericentromeric interstitial telomeric repeat (ITR) domains by restricting DNA accessibility to Telomere Repeat Binding (TRB) proteins, a group of H1-related Myb factors mediating PRC2 cis recruitment. This study provides a mechanistic framework by which H1 avoids the formation of gigantic H3K27me3-rich domains at telomeric sequences and contributes to safeguard nucleus architecture.
ER  -

TEANO, Gianluca, Lorenzo CONCIA, Lea WOLFF, Leopold CARRON, Ivona BIOCANIN, Kateřina ADAMUSOVÁ, Miloslava FOJTOVÁ, Michael BOURGE, Amira KRAMDI, Vincent COLOT, Ueli GROSSNIKLAUS, Chris BOWLER, Celia BAROUX, Alessandra CARBONE, Aline V PROBST, Petra PROCHÁZKOVÁ SCHRUMPFOVÁ, Jiří FAJKUS, Simon AMIARD, Stefan GROB, Clara BOURBOUSSE a Fredy BARNECHE. Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis. \textit{Cell Reports}. Elsevier, 2023, roč.~42, č.~8, s.~1-23. ISSN~2211-1247. Dostupné z: https://dx.doi.org/10.1016/j.celrep.2023.112894.

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