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@proceedings{2373178, author = {Čimborová, Katarína and Pelková, Vendula and Kotasová, Hana and Sedláková, Veronika and Hampl, Aleš}, booktitle = {BIOCEV Regeneration III, 2023}, title = {Decellularization of lung to yield three-dimensional scaffold for pulmonary tissue engineering}, url = {https://www.iem.cas.cz/events/biocev-regeneration-2023/}, year = {2023} }
TY - CONF ID - 2373178 AU - Čimborová, Katarína - Pelková, Vendula - Kotasová, Hana - Sedláková, Veronika - Hampl, Aleš PY - 2023 TI - Decellularization of lung to yield three-dimensional scaffold for pulmonary tissue engineering UR - https://www.iem.cas.cz/events/biocev-regeneration-2023/ N2 - The structural and physiological features of the lungs make the success of engineering an artificial lung model in vitro a challenge. From a slew of approaches utilized in pulmonary tissue engineering, this work focuses on the detergent-based decellularization method for obtaining a well-preserved human, pig, and mouse lung tissue scaffold. Decellularization is a method based on removing cells and the entire genetic material from a preexisting organ or tissue while preserving the composition, 3D microarchitecture, and biochemical and biophysical properties of the pulmonary tissue. These scaffolds may serve as in vitro near-to-native 3D pulmonary models, hydrogels, or bio-inks for 3D printing which hold a valuable opportunity for disease modeling, drug testing, and regeneration. ER -
ČIMBOROVÁ, Katarína, Vendula PELKOVÁ, Hana KOTASOVÁ, Veronika SEDLÁKOVÁ a Aleš HAMPL. Decellularization of lung to yield three-dimensional scaffold for pulmonary tissue engineering. In \textit{BIOCEV Regeneration III, 2023}. 2023.
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