Cycles of satellite and transposon evolution in
Arabidopsis centromeres

J 2023

Cycles of satellite and transposon evolution in Arabidopsis centromeres

WLODZIMIERZ, Piotr, Fernando A RABANAL, Robin BURNS, Matthew NAISH, Elias PRIMETIS et. al.

Basic information

Original name

Cycles of satellite and transposon evolution in Arabidopsis centromeres

Authors

WLODZIMIERZ, Piotr, Fernando A RABANAL, Robin BURNS, Matthew NAISH, Elias PRIMETIS, Alison SCOTT, Terezie MALÍK MANDÁKOVÁ (203 Czech Republic, belonging to the institution), Nicola GORRINGE, Andrew J TOCK, Daniel HOLLAND, Katrin FRITSCHI, Anette HABRING, Christa LANZ, Christie PATEL, Theresa SCHLEGEL, Maximilian COLLENBERG, Miriam MIELKE, Magnus NORDBORG, Fabrice ROUX, Gautam SHIRSEKAR, Carlos ALONSO-BLANCO, Martin LYSÁK (203 Czech Republic, belonging to the institution), Polina Y NOVIKOVA, Alexandros BOUSIOS, Detlef WEIGEL and Ian R HENDERSON (guarantor)

Edition

Nature, BERLIN, NATURE PORTFOLIO, 2023, 0028-0836

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10611 Plant sciences, botany

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 64.800 in 2022

RIV identification code

RIV/00216224:14740/23:00134414

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1038/s41586-023-06062-z

UT WoS

000991386800003

Keywords in English

CONCERTED EVOLUTION; SELF-INCOMPATIBILITY; SEQUENCE; DNA THALIANALYRATA; HOMOGENIZATION; RECOMBINATION; ANNOTATION; ALIGNMENT

Abstract

V originále

Centromeres are critical for cell division, loading CENH3 or CENPA histone variant nucleosomes, directing kinetochore formation and allowing chromosome segregation(1,2). Despite their conserved function, centromere size and structure are diverse across species. To understand this centromere paradox(3,4), it is necessary to know how centromeric diversity is generated and whether it reflects ancient trans-species variation or, instead, rapid post-speciation divergence. To address these questions, we assembled 346 centromeres from 66 Arabidopsis thaliana and 2 Arabidopsis lyrata accessions, which exhibited a remarkable degree of intra- and inter-species diversity. A. thaliana centromere repeat arrays are embedded in linkage blocks, despite ongoing internal satellite turnover, consistent with roles for unidirectional gene conversion or unequal crossover between sister chromatids in sequence diversification. Additionally, centrophilic ATHILA transposons have recently invaded the satellite arrays. To counter ATHILA invasion, chromosome-specific bursts of satellite homogenization generate higher-order repeats and purge transposons, in line with cycles of repeat evolution. Centromeric sequence changes are even more extreme in comparison between A. thaliana and A. lyrata. Together, our findings identify rapid cycles of transposon invasion and purging through satellite homogenization, which drive centromere evolution and ultimately contribute to speciation.

Links

GA21-03909S, research and development project

Name: Odhalení evolučních tajů lničky seté a příbuzných druhů

Investor: Czech Science Foundation, Unlocking evolutionary secrets of false flax and its relatives

Citovat

WLODZIMIERZ, Piotr, Fernando A RABANAL, Robin BURNS, Matthew NAISH, Elias PRIMETIS, Alison SCOTT, Terezie MALÍK MANDÁKOVÁ, Nicola GORRINGE, Andrew J TOCK, Daniel HOLLAND, Katrin FRITSCHI, Anette HABRING, Christa LANZ, Christie PATEL, Theresa SCHLEGEL, Maximilian COLLENBERG, Miriam MIELKE, Magnus NORDBORG, Fabrice ROUX, Gautam SHIRSEKAR, Carlos ALONSO-BLANCO, Martin LYSÁK, Polina Y NOVIKOVA, Alexandros BOUSIOS, Detlef WEIGEL and Ian R HENDERSON. Cycles of satellite and transposon evolution in Arabidopsis centromeres. Nature. BERLIN: NATURE PORTFOLIO, 2023, vol. 618, No 7965, p. 1-34. ISSN 0028-0836. Available from: https://dx.doi.org/10.1038/s41586-023-06062-z.

@article{2376999,
 author = {Wlodzimierz, Piotr and Rabanal, Fernando A and Burns, Robin and Naish, Matthew and Primetis, Elias and Scott, Alison and Malík Mandáková, Terezie and Gorringe, Nicola and Tock, Andrew J and Holland, Daniel and Fritschi, Katrin and Habring, Anette and Lanz, Christa and Patel, Christie and Schlegel, Theresa and Collenberg, Maximilian and Mielke, Miriam and Nordborg, Magnus and Roux, Fabrice and Shirsekar, Gautam and AlonsoandBlanco, Carlos and Lysák, Martin and Novikova, Polina Y and Bousios, Alexandros and Weigel, Detlef and Henderson, Ian R},
 article_location = {BERLIN},
 article_number = {7965},
 doi = {http://dx.doi.org/10.1038/s41586-023-06062-z},
 keywords = {CONCERTED EVOLUTION; SELF-INCOMPATIBILITY; SEQUENCE; DNA THALIANALYRATA; HOMOGENIZATION; RECOMBINATION; ANNOTATION; ALIGNMENT},
 language = {eng},
 issn = {0028-0836},
 journal = {Nature},
 title = {Cycles of satellite and transposon evolution in Arabidopsis centromeres},
 url = {https://www.nature.com/articles/s41586-023-06062-z#citeas},
 volume = {618},
 year = {2023}
}

TY - JOUR
ID - 2376999
AU - Wlodzimierz, Piotr - Rabanal, Fernando A - Burns, Robin - Naish, Matthew - Primetis, Elias - Scott, Alison - Malík Mandáková, Terezie - Gorringe, Nicola - Tock, Andrew J - Holland, Daniel - Fritschi, Katrin - Habring, Anette - Lanz, Christa - Patel, Christie - Schlegel, Theresa - Collenberg, Maximilian - Mielke, Miriam - Nordborg, Magnus - Roux, Fabrice - Shirsekar, Gautam - Alonso-Blanco, Carlos - Lysák, Martin - Novikova, Polina Y - Bousios, Alexandros - Weigel, Detlef - Henderson, Ian R
PY - 2023
TI - Cycles of satellite and transposon evolution in Arabidopsis centromeres
JF - Nature
VL - 618
IS - 7965
SP - 1-34
EP - 1-34
PB - NATURE PORTFOLIO
SN - 00280836
KW - CONCERTED EVOLUTION
KW - SELF-INCOMPATIBILITY
KW - SEQUENCE
KW - DNA THALIANALYRATA
KW - HOMOGENIZATION
KW - RECOMBINATION
KW - ANNOTATION
KW - ALIGNMENT
UR - https://www.nature.com/articles/s41586-023-06062-z#citeas
N2 - Centromeres are critical for cell division, loading CENH3 or CENPA histone variant nucleosomes, directing kinetochore formation and allowing chromosome segregation(1,2). Despite their conserved function, centromere size and structure are diverse across species. To understand this centromere paradox(3,4), it is necessary to know how centromeric diversity is generated and whether it reflects ancient trans-species variation or, instead, rapid post-speciation divergence. To address these questions, we assembled 346 centromeres from 66 Arabidopsis thaliana and 2 Arabidopsis lyrata accessions, which exhibited a remarkable degree of intra- and inter-species diversity. A. thaliana centromere repeat arrays are embedded in linkage blocks, despite ongoing internal satellite turnover, consistent with roles for unidirectional gene conversion or unequal crossover between sister chromatids in sequence diversification. Additionally, centrophilic ATHILA transposons have recently invaded the satellite arrays. To counter ATHILA invasion, chromosome-specific bursts of satellite homogenization generate higher-order repeats and purge transposons, in line with cycles of repeat evolution. Centromeric sequence changes are even more extreme in comparison between A. thaliana and A. lyrata. Together, our findings identify rapid cycles of transposon invasion and purging through satellite homogenization, which drive centromere evolution and ultimately contribute to speciation.
ER -

WLODZIMIERZ, Piotr, Fernando A RABANAL, Robin BURNS, Matthew NAISH, Elias PRIMETIS, Alison SCOTT, Terezie MALÍK MANDÁKOVÁ, Nicola GORRINGE, Andrew J TOCK, Daniel HOLLAND, Katrin FRITSCHI, Anette HABRING, Christa LANZ, Christie PATEL, Theresa SCHLEGEL, Maximilian COLLENBERG, Miriam MIELKE, Magnus NORDBORG, Fabrice ROUX, Gautam SHIRSEKAR, Carlos ALONSO-BLANCO, Martin LYSÁK, Polina Y NOVIKOVA, Alexandros BOUSIOS, Detlef WEIGEL and Ian R HENDERSON. Cycles of satellite and transposon evolution in \&{}lt;i\&{}gt;Arabidopsis\&{}lt;/i\&{}gt; centromeres. \textit{Nature}. BERLIN: NATURE PORTFOLIO, 2023, vol.~618, No~7965, p.~1-34. ISSN~0028-0836. Available from: https://dx.doi.org/10.1038/s41586-023-06062-z.

Detailed Information on Publication Record

Cycles of satellite and transposon evolution in <i>Arabidopsis</i> centromeres