Comparison of different regimens of short-term antibiotic
prophylaxis in transrectal prostate biopsy

J 2024

Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy

KRSAKOVA, E., Aleš ČERMÁK a Michal FEDORKO

Základní údaje

Originální název

Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy

Autoři

KRSAKOVA, E. (203 Česká republika), Aleš ČERMÁK (203 Česká republika, domácí) a Michal FEDORKO (203 Česká republika, domácí)

Vydání

The Journal of hospital infection, W B SAUNDERS CO LTD, LONDON, 2024, 0195-6701

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30217 Urology and nephrology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.900 v roce 2022

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1016/j.jhin.2023.12.012

UT WoS

001181110700001

Klíčová slova anglicky

Antibiotic prophylaxis; Complications; Fosfomycin trometamol; Transrectal prostate biopsy

Štítky

14110225, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 10. 6. 2024 10:02, Mgr. Tereza Miškechová

Anotace

V originále

Background Prostate cancer is the most common malignant solid tumour in men aged >70 years and is the second most common cause of death from oncological circumstances. Aim To evaluate the effect of different short-term prophylactic antibiotic regimens in transrectal prostate biopsy (PB) on the incidence of infectious complications. Methods Patients who underwent transrectal ultrasound-guided PB between January 2021 and December 2022 were included in the prospective randomized study. According to the regimen of prophylaxis, patients were randomized into three groups: (1) fosfomycin trometamol 3 g, 3 h before the procedure + ciprofloxacin 500 mg, 2 h before the procedure; (2) fosfomycin trometamol 3 g, 3 h before and 24 h after the procedure; (3) ciprofloxacin 500 mg 12, 2 h before the procedure, and 12 h after the procedure. A rectal swab was performed 1–2 weeks before PB to evaluate the culture findings. Complications were evaluated during follow-up visits within one month after PB. Findings In the monitored period, 605 PBs were performed, and 544 patients met the inclusion criteria (184, 161, and 199 in groups 1, 2, and 3). Infectious complications occurred in 10 cases (1.83%), namely 3, 4, and 3 according to patient groups. There was no statistically significant difference between the individual groups. None of the patients required hospitalization and all were free of symptoms of sepsis. Conclusion Short-term antibiotic prophylaxis in PB using fosfomycin trometamol, ciprofloxacin, or their combination appears to be effective. Fosfomycin trometamol is a suitable alternative to fluoroquinolone antibiotics.

Citovat

KRSAKOVA, E., Aleš ČERMÁK a Michal FEDORKO. Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy. The Journal of hospital infection. W B SAUNDERS CO LTD: LONDON, 2024, roč. 145, March 2024, s. 83-87. ISSN 0195-6701. Dostupné z: https://dx.doi.org/10.1016/j.jhin.2023.12.012.

@article{2377521,
   author = {Krsakova, E. and Čermák, Aleš and Fedorko, Michal},
   article_location = {W B SAUNDERS CO LTD},
   article_number = {March 2024},
   doi = {http://dx.doi.org/10.1016/j.jhin.2023.12.012},
   keywords = {Antibiotic prophylaxis; Complications; Fosfomycin trometamol; Transrectal prostate biopsy},
   language = {eng},
   issn = {0195-6701},
   journal = {The Journal of hospital infection},
   title = {Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy},
   url = {https://www.journalofhospitalinfection.com/article/S0195-6701(24)00003-3/fulltext#%20},
   volume = {145},
   year = {2024}
}

TY  - JOUR
ID  - 2377521
AU  - Krsakova, E. - Čermák, Aleš - Fedorko, Michal
PY  - 2024
TI  - Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy
JF  - The Journal of hospital infection
VL  - 145
IS  - March 2024
SP  - 83-87
EP  - 83-87
PB  - LONDON
SN  - 01956701
KW  - Antibiotic prophylaxis
KW  - Complications
KW  - Fosfomycin trometamol
KW  - Transrectal prostate biopsy
UR  - https://www.journalofhospitalinfection.com/article/S0195-6701(24)00003-3/fulltext#%20
N2  - Background Prostate cancer is the most common malignant solid tumour in men aged >70 years and is the second most common cause of death from oncological circumstances. Aim To evaluate the effect of different short-term prophylactic antibiotic regimens in transrectal prostate biopsy (PB) on the incidence of infectious complications. Methods Patients who underwent transrectal ultrasound-guided PB between January 2021 and December 2022 were included in the prospective randomized study. According to the regimen of prophylaxis, patients were randomized into three groups: (1) fosfomycin trometamol 3 g, 3 h before the procedure + ciprofloxacin 500 mg, 2 h before the procedure; (2) fosfomycin trometamol 3 g, 3 h before and 24 h after the procedure; (3) ciprofloxacin 500 mg 12, 2 h before the procedure, and 12 h after the procedure. A rectal swab was performed 1–2 weeks before PB to evaluate the culture findings. Complications were evaluated during follow-up visits within one month after PB. Findings In the monitored period, 605 PBs were performed, and 544 patients met the inclusion criteria (184, 161, and 199 in groups 1, 2, and 3). Infectious complications occurred in 10 cases (1.83%), namely 3, 4, and 3 according to patient groups. There was no statistically significant difference between the individual groups. None of the patients required hospitalization and all were free of symptoms of sepsis. Conclusion Short-term antibiotic prophylaxis in PB using fosfomycin trometamol, ciprofloxacin, or their combination appears to be effective. Fosfomycin trometamol is a suitable alternative to fluoroquinolone antibiotics.
ER  -

KRSAKOVA, E., Aleš ČERMÁK a Michal FEDORKO. Comparison of different regimens of short-term antibiotic prophylaxis in transrectal prostate biopsy. \textit{The Journal of hospital infection}. W B SAUNDERS CO LTD: LONDON, 2024, roč.~145, March 2024, s.~83-87. ISSN~0195-6701. Dostupné z: https://dx.doi.org/10.1016/j.jhin.2023.12.012.

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