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@article{2379798,
author = {Ambrosioni, Juan and HernandezandMeneses, Marta and DuranteandMangoni, Emanuele and Tattevin, Pierre and Olaison, Lars and Freiberger, Tomáš and Hurley, John and Hannan, Margaret M and Chu, Vivian and Hoen, Bruno and Moreno, Asuncion and Cuervo, Guillermo and Llopis, Jaume and Miro, Jose M},
article_location = {London},
article_number = {4},
doi = {http://dx.doi.org/10.1007/s40121-023-00763-8},
keywords = {Infective endocarditis; Europe; Epidemiology; Cardiac surgery; Mortality},
language = {eng},
issn = {2193-8229},
journal = {INFECTIOUS DISEASES AND THERAPY},
title = {Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000-2012)},
url = {https://link.springer.com/article/10.1007/s40121-023-00763-8},
volume = {12},
year = {2023}
}
TY - JOUR
ID - 2379798
AU - Ambrosioni, Juan - Hernandez-Meneses, Marta - Durante-Mangoni, Emanuele - Tattevin, Pierre - Olaison, Lars - Freiberger, Tomáš - Hurley, John - Hannan, Margaret M - Chu, Vivian - Hoen, Bruno - Moreno, Asuncion - Cuervo, Guillermo - Llopis, Jaume - Miro, Jose M
PY - 2023
TI - Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000-2012)
JF - INFECTIOUS DISEASES AND THERAPY
VL - 12
IS - 4
SP - 1083-1101
EP - 1083-1101
PB - SPRINGER LONDON LTD
SN - 21938229
KW - Infective endocarditis
KW - Europe
KW - Epidemiology
KW - Cardiac surgery
KW - Mortality
UR - https://link.springer.com/article/10.1007/s40121-023-00763-8
N2 - Introduction Infective endocarditis (IE) has undergone important changes in its epidemiology worldwide.Methods The study aimed to compare IE epidemiological features and outcomes according to predefined European regions and between two different time periods in the twenty-first century.Results IE cases from 13 European countries were included. Two periods were considered: 2000-2006 and 2008-2012. Two European regions were considered, according to the United Nations geoscheme for Europe: Southern (SE) and Northern-Central Europe (NCE). Comparisons were performed between regions and periods. A total of 4195 episodes of IE were included, 2113 from SE and 2082 from NCE; 2787 cases were included between 2000 and 2006 and 1408 between 2008 and 2012. Median (IQR) age was 63.7 (49-74) years and 69.4% were males. Native valve IE (NVE), prosthetic valve IE (PVE), and device-related IE were diagnosed in 68.3%, 23.9%, and 7.8% of cases, respectively; 52% underwent surgery and 19.3% died during hospitalization. NVE was more prevalent in NCE, whereas device-related IE was more frequent in SE. Higher age, acute presentation, hemodialysis, cancer, and diabetes mellitus all were more prevalent in the second period. NVE decreased and PVE and device-related IE both increased in the second period. Surgical treatment also increased from 48.7% to 58.4% (p < 0.01). In-hospital and 6-month mortality rates were comparable between regions and significantly decreased in the second period.Conclusions Despite an increased complexity of IE cases, prognosis improved in recent years with a significant decrease in 6-month mortality. Outcome did not differ according to the European region (SE versus NCE).
ER -
AMBROSIONI, Juan, Marta HERNANDEZ-MENESES, Emanuele DURANTE-MANGONI, Pierre TATTEVIN, Lars OLAISON, Tomáš FREIBERGER, John HURLEY, Margaret M HANNAN, Vivian CHU, Bruno HOEN, Asuncion MORENO, Guillermo CUERVO, Jaume LLOPIS a Jose M MIRO. Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000-2012). \textit{INFECTIOUS DISEASES AND THERAPY}. London: SPRINGER LONDON LTD, 2023, roč.~12, č.~4, s.~1083-1101. ISSN~2193-8229. Dostupné z: https://dx.doi.org/10.1007/s40121-023-00763-8.
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