Understanding the Relationship of the Human Bacteriome with
COVID-19 Severity and Recovery

J 2023

Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery

ZAFAR, Hassan a Jr Milton, H. SAIER

Základní údaje

Originální název

Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery

Autoři

ZAFAR, Hassan (586 Pákistán, garant, domácí) a Jr Milton, H. SAIER

Vydání

Advances in Fuel Cells, BASEL, Elsevier, 2023, 2073-4409

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10601 Cell biology

Stát vydavatele

Švýcarsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 6.000 v roce 2022

Kód RIV

RIV/00216224:14740/23:00133743

Organizační jednotka

Středoevropský technologický institut

DOI

http://dx.doi.org/10.3390/cells12091213

UT WoS

000987178700001

Klíčová slova anglicky

SARS-CoV-2; COVID-19; bacteriome; immune system

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 8. 2024 10:09, Mgr. Eva Dubská

Anotace

V originále

The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) first emerged in 2019 in China and has resulted in millions of human morbidities and mortalities across the globe. Evidence has been provided that this novel virus originated in animals, mutated, and made the cross-species jump to humans. At the time of this communication, the Coronavirus disease (COVID-19) may be on its way to an endemic form; however, the threat of the virus is more for susceptible (older and immunocompromised) people. The human body has millions of bacterial cells that influence health and disease. As a consequence, the bacteriomes in the human body substantially influence human health and disease. The bacteriomes in the body and the immune system seem to be in constant association during bacterial and viral infections. In this review, we identify various bacterial spp. In major bacteriomes (oral, nasal, lung, and gut) of the body in healthy humans and compare them with dysbiotic bacteriomes of COVID-19 patients. We try to identify key bacterial spp. That have a positive effect on the functionality of the immune system and human health. These select bacterial spp. Could be used as potential probiotics to counter or prevent COVID-19 infections. In addition, we try to identify key metabolites produced by probiotic bacterial spp. That could have potential anti-viral effects against SARS-CoV-2. These metabolites could be subject to future therapeutic trials to determine their anti-viral efficacies.

Citovat

ZAFAR, Hassan a Jr Milton, H. SAIER. Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery. Advances in Fuel Cells. BASEL: Elsevier, 2023, roč. 12, č. 9, s. 1-31. ISSN 2073-4409. Dostupné z: https://dx.doi.org/10.3390/cells12091213.

@article{2382439,
   author = {Zafar, Hassan and Saier, Jr Milton, H.},
   article_location = {BASEL},
   article_number = {9},
   doi = {http://dx.doi.org/10.3390/cells12091213},
   keywords = {SARS-CoV-2; COVID-19; bacteriome; immune system},
   language = {eng},
   issn = {2073-4409},
   journal = {Advances in Fuel Cells},
   title = {Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery},
   url = {https://www.mdpi.com/2073-4409/12/9/1213},
   volume = {12},
   year = {2023}
}

TY  - JOUR
ID  - 2382439
AU  - Zafar, Hassan - Saier, Jr Milton, H.
PY  - 2023
TI  - Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery
JF  - Advances in Fuel Cells
VL  - 12
IS  - 9
SP  - 1-31
EP  - 1-31
PB  - Elsevier
SN  - 20734409
KW  - SARS-CoV-2
KW  - COVID-19
KW  - bacteriome
KW  - immune system
UR  - https://www.mdpi.com/2073-4409/12/9/1213
N2  - The Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) first emerged in 2019 in China and has resulted in millions of human morbidities and mortalities across the globe. Evidence has been provided that this novel virus originated in animals, mutated, and made the cross-species jump to humans. At the time of this communication, the Coronavirus disease (COVID-19) may be on its way to an endemic form; however, the threat of the virus is more for susceptible (older and immunocompromised) people. The human body has millions of bacterial cells that influence health and disease. As a consequence, the bacteriomes in the human body substantially influence human health and disease. The bacteriomes in the body and the immune system seem to be in constant association during bacterial and viral infections. In this review, we identify various bacterial spp. In major bacteriomes (oral, nasal, lung, and gut) of the body in healthy humans and compare them with dysbiotic bacteriomes of COVID-19 patients. We try to identify key bacterial spp. That have a positive effect on the functionality of the immune system and human health. These select bacterial spp. Could be used as potential probiotics to counter or prevent COVID-19 infections. In addition, we try to identify key metabolites produced by probiotic bacterial spp. That could have potential anti-viral effects against SARS-CoV-2. These metabolites could be subject to future therapeutic trials to determine their anti-viral efficacies.
ER  -

ZAFAR, Hassan a Jr Milton, H. SAIER. Understanding the Relationship of the Human Bacteriome with COVID-19 Severity and Recovery. \textit{Advances in Fuel Cells}. BASEL: Elsevier, 2023, roč.~12, č.~9, s.~1-31. ISSN~2073-4409. Dostupné z: https://dx.doi.org/10.3390/cells12091213.

Podrobný výpis o publikaci