2024
Influence of metabolic state and body composition on the action of pharmacological treatment of migraine
BRUIJN, Noor, van Lohuizen ROMY, Malgorzata BORON, Mira FITZEK, Francesca GABRIELE et. al.Základní údaje
Originální název
Influence of metabolic state and body composition on the action of pharmacological treatment of migraine
Autoři
BRUIJN, Noor, van Lohuizen ROMY, Malgorzata BORON, Mira FITZEK, Francesca GABRIELE, Giada GIULIANI, Laura MELGAREJO, Pavel ŘEHULKA (203 Česká republika, domácí), Gabriele SEBASTIANELLI, Paul TRILLER, Simone VIGNERI, Behiye OZCAN a van den Brink Antoinette MAASSEN
Vydání
JOURNAL OF HEADACHE AND PAIN, LONDON, BMC, 2024, 1129-2369
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30210 Clinical neurology
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 7.400 v roce 2022
Organizační jednotka
Lékařská fakulta
UT WoS
001160025300001
Klíčová slova anglicky
CGRP; Metabolic disorders; Diabetes mellitus; Migraine; Obesity; Lifestyle
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 29. 4. 2024 14:09, Mgr. Tereza Miškechová
Anotace
V originále
Migraine is a disabling neurovascular disorder among people of all ages, with the highest prevalence in the fertile years, and in women. Migraine impacts the quality of life of affected individuals tremendously and, in addition, it is associated with highly prevalent metabolic diseases, such as obesity, diabetes mellitus and thyroid dysfunction. Also, the clinical response to drugs might be affected in patients with metabolic disease due to body composition and metabolic change. Therefore, the efficacy of antimigraine drugs could be altered in patients with both migraine and metabolic disease. However, knowledge of the pharmacology and the related clinical effects of antimigraine drugs in patients with metabolic disease are limited. Therefore, and given the clinical relevance, this article provides a comprehensive overview of the current research and hypotheses related to the influence of metabolic state and body composition on the action of antimigraine drugs. In addition, the influence of antimigraine drugs on metabolic functioning and, vice versa, the influence of metabolic diseases and its hormonal modulating medication on migraine activity is outlined. Future exploration on personalizing migraine treatment to individual characteristics is necessary to enhance therapeutic strategies, especially given its increasing significance in recent decades.
Návaznosti
LM2023049, projekt VaV |
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