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@article{2408018,
author = {Horák, Tomáš and Horáková, Magda and Keřkovský, Miloš and Dostál, Marek and Hlustik, Petr and Valosek, Jan and Svatkova, Alena and Bednarik, Petr and Vlčková, Eva and Bednařík, Josef},
article_location = {Lausanne},
article_number = {May 2024},
doi = {http://dx.doi.org/10.3389/fneur.2024.1341371},
keywords = {degenerative cervical cord compression; degenerative cervical myelopathy; cervical spinal canal stenosis; magnetic resonance imaging; subclinical myelopathy},
language = {eng},
issn = {1664-2295},
journal = {Frontiers in Neurology},
title = {Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy},
url = {https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1341371/full},
volume = {15},
year = {2024}
}
TY - JOUR
ID - 2408018
AU - Horák, Tomáš - Horáková, Magda - Keřkovský, Miloš - Dostál, Marek - Hlustik, Petr - Valosek, Jan - Svatkova, Alena - Bednarik, Petr - Vlčková, Eva - Bednařík, Josef
PY - 2024
TI - Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy
JF - Frontiers in Neurology
VL - 15
IS - May 2024
SP - 1-9
EP - 1-9
PB - Frontiers
SN - 16642295
KW - degenerative cervical cord compression
KW - degenerative cervical myelopathy
KW - cervical spinal canal stenosis
KW - magnetic resonance imaging
KW - subclinical myelopathy
UR - https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2024.1341371/full
N2 - Degenerative cervical myelopathy (DCM) represents the final consequence of a series of degenerative changes in the cervical spine, resulting in cervical spinal canal stenosis and mechanical stress on the cervical spinal cord. This process leads to subsequent pathophysiological processes in the spinal cord tissues. The primary mechanism of injury is degenerative compression of the cervical spinal cord, detectable by magnetic resonance imaging (MRI), serving as a hallmark for diagnosing DCM. However, the relative resilience of the cervical spinal cord to mechanical compression leads to clinical-radiological discordance, i.e., some individuals may exhibit MRI findings of DCC without the clinical signs and symptoms of myelopathy. This degenerative compression of the cervical spinal cord without clinical signs of myelopathy, potentially serving as a precursor to the development of DCM, remains a somewhat controversial topic. In this review article, we elaborate on and provide commentary on the terminology, epidemiology, natural course, diagnosis, predictive value, risks, and practical management of this condition-all of which are subjects of ongoing debate.
ER -
HORÁK, Tomáš, Magda HORÁKOVÁ, Miloš KEŘKOVSKÝ, Marek DOSTÁL, Petr HLUSTIK, Jan VALOSEK, Alena SVATKOVA, Petr BEDNARIK, Eva VLČKOVÁ a Josef BEDNAŘÍK. Evidence-based commentary on the diagnosis, management, and further research of degenerative cervical spinal cord compression in the absence of clinical symptoms of myelopathy. \textit{Frontiers in Neurology}. Lausanne: Frontiers, 2024, roč.~15, May 2024, s.~1-9. ISSN~1664-2295. Dostupné z: https://dx.doi.org/10.3389/fneur.2024.1341371.
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