J 2024

Roles of spectral dual-layer CT, D-dimer concentration, and COVID-19 pneumonia in diagnosis of pulmonary embolism

JŮZA, Tomáš, Vlastimil VÁLEK, Daniel VLK, Marek DOSTÁL, Tomáš ANDRAŠINA et. al.

Basic information

Original name

Roles of spectral dual-layer CT, D-dimer concentration, and COVID-19 pneumonia in diagnosis of pulmonary embolism

Authors

JŮZA, Tomáš (203 Czech Republic, guarantor, belonging to the institution), Vlastimil VÁLEK (203 Czech Republic, belonging to the institution), Daniel VLK (203 Czech Republic, belonging to the institution), Marek DOSTÁL (203 Czech Republic, belonging to the institution) and Tomáš ANDRAŠINA (703 Slovakia, belonging to the institution)

Edition

EUROPEAN JOURNAL OF RADIOLOGY OPEN, AMSTERDAM, ELSEVIER, 2024, 2352-0477

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30224 Radiology, nuclear medicine and medical imaging

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 2.000 in 2022

Organization unit

Faculty of Medicine

DOI

UT WoS

001255351100001

Keywords (in Czech)

Spektrální CT; Dual-energy CT; Plicní embolie; COVID-19; D-dimer

Keywords in English

Spectral CT; Dual-energy CT; Pulmonary embolism; COVID-19; D-dimer

Tags

Tags

International impact, Reviewed
Změněno: 9/7/2024 08:51, Mgr. Tereza Miškechová

Abstract

V originále

In the past few years, we have seen increasing demand for computer tomography pulmonary angiographies (CTPAs) intended to rule out pulmonary embolism (PE). Such requests even escalated during the COVID-19 pandemic. Beyond clinical symptoms, increased plasmatic D-dimer concentration was the main reason for CTPA requests. We decided to investigate and confirm the role of D-dimer concentration in PE diagnosis to help in optimizing requests from clinicians. We had recently installed spectral dual-layer CT and so we asked, from a radiologist’s point of view, how does this technology help us to detect PE? In this paper, we present a retrospective cross-sectional study of three groups of computer tomography pulmonary angiographies (500 in each group) conducted in our hospital. The first group of patients underwent scans by conventional multidetector CT, the second group by dual-layer spectral CT, and the third by dual-layer spectral CT after having tested positive for COVID-19 test and showing CT signs of viral pneumonia. We compared prevalence of pulmonary embolism, inconclusive pulmonary embolism findings, and plasmatic D-dimer concentrations with reference to presence and extent of pulmonary embolism among each group. We confirmed increased level of D-dimer in cases with PE. In patients COVID-19 negative, D-dimer levels were also higher in cases with more extensive PE. In patients with COVID-19 pneumonia, the usual threshold of 0.5 mg/L D-dimer concentration could be doubled while maintaining 100% sensitivity. Techniques of spectral CT helped us to reduce the number of inconclusive PE findings.