Destructive nanoindentation techniques to study biological
membranes

D 2024

Destructive nanoindentation techniques to study biological membranes

PŘIBYL, Jan, Radka OBOŘILOVÁ, Jakub HRUŠKA, Lucie VÁLKOVÁ, Jan KOLÁČEK et. al.

Základní údaje

Originální název

Destructive nanoindentation techniques to study biological membranes

Autoři

PŘIBYL, Jan (203 Česká republika, domácí), Radka OBOŘILOVÁ (203 Česká republika, domácí), Jakub HRUŠKA (203 Česká republika, domácí), Lucie VÁLKOVÁ (203 Česká republika, domácí), Jan KOLÁČEK (203 Česká republika, domácí), Ondřej POKORA (203 Česká republika, domácí), Jan SLOVÁK (203 Česká republika, domácí) a Monika PÁVKOVÁ GOLDBERGOVÁ (203 Česká republika, domácí)

Vydání

Ostrava, Proceedings 15th International Conference on Nanomaterials - Research & Application, od s. 347-352, 6 s. 2024

Nakladatel

TANGER Ltd.

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

21001 Nano-materials

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

elektronická verze "online"

Odkazy

URL

Organizační jednotka

Středoevropský technologický institut

ISBN

978-80-88365-15-0

ISSN

DOI

http://dx.doi.org/10.37904/nanocon.2023.4764

UT WoS

001234125400055

Klíčová slova anglicky

Phospholipid bilayers; Atomic Force Microscopy; Force-Distance Curves; Smoothing splines; Local extrema

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 8. 2024 13:13, Mgr. Tereza Miškechová

Anotace

V originále

Atomic Force Microscopy (AFM) belongs to the nanoimaging methods employing the fine driving of the probe movement, where its interaction with the sample gives a detailed view of the surface structure. The ability to control the motion of the sample and thus its force interaction with the surface provides the possibility to map the sample's mechanical properties at the nanoscale, but also, for example, to influence the sample, even destructively, which can provide further interesting information. AFM ability to study the structure of biological molecules is here represented by the supported lipid bilayer (SLB), a synthetic model for cellular membranes. The traditional approach of SLB structural study can be extended by the destructive use of AFM probe, penetrating through the solid structure of the double layer, leaving a typical pattern in the measured curves. The characteristics of this mark then help in the detailed characterisation of the mechanical properties of this synthetic membrane in particular.

Návaznosti

LM2023042, projekt VaV

Název: Česká infrastruktura pro integrativní strukturní biologii

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, CIISB - Česká infrastruktura pro integrativní strukturní biologii

MUNI/G/1125/2022, interní kód MU

Název: Machine Learning in Nanomaterial Biocompatibility Assessment

Investor: Masarykova univerzita, Machine Learning in Nanomaterial Biocompatibility Assessment, INTERDISCIPLINARY - Mezioborové výzkumné projekty

Citovat

PŘIBYL, Jan, Radka OBOŘILOVÁ, Jakub HRUŠKA, Lucie VÁLKOVÁ, Jan KOLÁČEK, Ondřej POKORA, Jan SLOVÁK a Monika PÁVKOVÁ GOLDBERGOVÁ. Destructive nanoindentation techniques to study biological membranes. Online. In Proceedings 15th International Conference on Nanomaterials - Research & Application. Ostrava: TANGER Ltd., 2024, s. 347-352. ISBN 978-80-88365-15-0. Dostupné z: https://dx.doi.org/10.37904/nanocon.2023.4764.

@inproceedings{2413663,
   author = {Přibyl, Jan and Obořilová, Radka and Hruška, Jakub and Válková, Lucie and Koláček, Jan and Pokora, Ondřej and Slovák, Jan and Pávková Goldbergová, Monika},
   address = {Ostrava},
   booktitle = {Proceedings 15th International Conference on Nanomaterials - Research & Application},
   doi = {http://dx.doi.org/10.37904/nanocon.2023.4764},
   keywords = {Phospholipid bilayers; Atomic Force Microscopy; Force-Distance Curves; Smoothing splines; Local extrema},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {Ostrava},
   isbn = {978-80-88365-15-0},
   pages = {347-352},
   publisher = {TANGER Ltd.},
   title = {Destructive nanoindentation techniques to study biological membranes},
   url = {https://www.confer.cz/nanocon/2023/4764-destructive-nanoindentation-techniques-to-study-biological-membranes},
   year = {2024}
}

TY  - JOUR
ID  - 2413663
AU  - Přibyl, Jan - Obořilová, Radka - Hruška, Jakub - Válková, Lucie - Koláček, Jan - Pokora, Ondřej - Slovák, Jan - Pávková Goldbergová, Monika
PY  - 2024
TI  - Destructive nanoindentation techniques to study biological membranes
PB  - TANGER Ltd.
CY  - Ostrava
SN  - 9788088365150
KW  - Phospholipid bilayers
KW  - Atomic Force Microscopy
KW  - Force-Distance Curves
KW  - Smoothing splines
KW  - Local extrema
UR  - https://www.confer.cz/nanocon/2023/4764-destructive-nanoindentation-techniques-to-study-biological-membranes
N2  - Atomic Force Microscopy (AFM) belongs to the nanoimaging methods employing the fine driving of the probe movement, where its interaction with the sample gives a detailed view of the surface structure. The ability to control the motion of the sample and thus its force interaction with the surface provides the possibility to map the sample's mechanical properties at the nanoscale, but also, for example, to influence the sample, even destructively, which can provide further interesting information. AFM ability to study the structure of biological molecules is here represented by the supported lipid bilayer (SLB), a synthetic model for cellular membranes. The traditional approach of SLB structural study can be extended by the destructive use of AFM probe, penetrating through the solid structure of the double layer, leaving a typical pattern in the measured curves. The characteristics of this mark then help in the detailed characterisation of the mechanical properties of this synthetic membrane in particular.
ER  -

PŘIBYL, Jan, Radka OBOŘILOVÁ, Jakub HRUŠKA, Lucie VÁLKOVÁ, Jan KOLÁČEK, Ondřej POKORA, Jan SLOVÁK a Monika PÁVKOVÁ GOLDBERGOVÁ. Destructive nanoindentation techniques to study biological membranes. Online. In \textit{Proceedings 15th International Conference on Nanomaterials - Research \&{} Application}. Ostrava: TANGER Ltd., 2024, s.~347-352. ISBN~978-80-88365-15-0. Dostupné z: https://dx.doi.org/10.37904/nanocon.2023.4764.

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