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@inproceedings{2413663,
author = {Přibyl, Jan and Obořilová, Radka and Hruška, Jakub and Válková, Lucie and Koláček, Jan and Pokora, Ondřej and Slovák, Jan and Pávková Goldbergová, Monika},
address = {Ostrava},
booktitle = {Proceedings 15th International Conference on Nanomaterials - Research & Application},
doi = {http://dx.doi.org/10.37904/nanocon.2023.4764},
keywords = {Phospholipid bilayers; Atomic Force Microscopy; Force-Distance Curves; Smoothing splines; Local extrema},
howpublished = {elektronická verze "online"},
language = {eng},
location = {Ostrava},
isbn = {978-80-88365-15-0},
pages = {347-352},
publisher = {TANGER Ltd.},
title = {Destructive nanoindentation techniques to study biological membranes},
url = {https://www.confer.cz/nanocon/2023/4764-destructive-nanoindentation-techniques-to-study-biological-membranes},
year = {2023}
}
TY - JOUR
ID - 2413663
AU - Přibyl, Jan - Obořilová, Radka - Hruška, Jakub - Válková, Lucie - Koláček, Jan - Pokora, Ondřej - Slovák, Jan - Pávková Goldbergová, Monika
PY - 2023
TI - Destructive nanoindentation techniques to study biological membranes
PB - TANGER Ltd.
CY - Ostrava
SN - 9788088365150
KW - Phospholipid bilayers
KW - Atomic Force Microscopy
KW - Force-Distance Curves
KW - Smoothing splines
KW - Local extrema
UR - https://www.confer.cz/nanocon/2023/4764-destructive-nanoindentation-techniques-to-study-biological-membranes
N2 - Atomic Force Microscopy (AFM) belongs to the nanoimaging methods employing the fine driving of the probe movement, where its interaction with the sample gives a detailed view of the surface structure. The ability to control the motion of the sample and thus its force interaction with the surface provides the possibility to map the sample's mechanical properties at the nanoscale, but also, for example, to influence the sample, even destructively, which can provide further interesting information. AFM ability to study the structure of biological molecules is here represented by the supported lipid bilayer (SLB), a synthetic model for cellular membranes. The traditional approach of SLB structural study can be extended by the destructive use of AFM probe, penetrating through the solid structure of the double layer, leaving a typical pattern in the measured curves. The characteristics of this mark then help in the detailed characterisation of the mechanical properties of this synthetic membrane in particular.
ER -
PŘIBYL, Jan, Radka OBOŘILOVÁ, Jakub HRUŠKA, Lucie VÁLKOVÁ, Jan KOLÁČEK, Ondřej POKORA, Jan SLOVÁK and Monika PÁVKOVÁ GOLDBERGOVÁ. Destructive nanoindentation techniques to study biological membranes. Online. In \textit{Proceedings 15th International Conference on Nanomaterials - Research \&{} Application}. Ostrava: TANGER Ltd., 2023, p.~347-352. ISBN~978-80-88365-15-0. Available from: https://dx.doi.org/10.37904/nanocon.2023.4764.
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