Training and education on inclusivity in clinical trials-the SENSITISE project

SHIELY, Frances, Jitka RYCHLÍČKOVÁ, Christine KUBIAK, Zora ČECHOVÁ, Martina ESDAILE a Shaun TREWEEK. Training and education on inclusivity in clinical trials-the SENSITISE project. Trials. LONDON: Elsevier, 2024, roč. 25, č. 1, s. 1-2. ISSN 1745-6215. Dostupné z: https://dx.doi.org/10.1186/s13063-024-08150-5.

Základní údaje

• Originální název: Training and education on inclusivity in clinical trials-the SENSITISE project
• Autoři: SHIELY, Frances, Jitka RYCHLÍČKOVÁ (203 Česká republika, domácí), Christine KUBIAK, Zora ČECHOVÁ (203 Česká republika, domácí), Martina ESDAILE a Shaun TREWEEK.
• Vydání: Trials, LONDON, Elsevier, 2024, 1745-6215.

Další údaje

• Originální jazyk: angličtina
• Typ výsledku: Článek v odborném periodiku
• Obor: 30230 Other clinical medicine subjects
• Stát vydavatele: Velká Británie a Severní Irsko
• Utajení: není předmětem státního či obchodního tajemství
• WWW: URL
• Impakt faktor: Impact factor: 2.500 v roce 2022
• Organizační jednotka: Lékařská fakulta
• Doi: http://dx.doi.org/10.1186/s13063-024-08150-5
• UT WoS: 001222713100001
• Klíčová slova anglicky: clinical trials; training; education
• Štítky: 14110516, rivok
• Příznaky: Mezinárodní význam, Recenzováno

Anotace

There have been calls globally to improve participation in clinical trials of groups that traditionally have been under-represented. These under-served groups are populations under-represented or disengaged from medical research or services despite having a disproportionately high healthcare burden. INCLUDE, a 2017 initiative from the UK’s National Institute of Health Research (NIHR), has defined and identified under-served groups in clinical trials (elderly, ethnic minorities, the socioeconomically disadvantaged, pregnant and lactating women, the LGBTQ+ community, rural dwellers, those with comorbidities including disability, mental health conditions or cognitive impairment, amongst others) and barriers for recruitment. Trial conclusions cannot with certainty support treatment decisions (or mode of treatment delivery) for those not represented in the trial. This perpetuates inequality, is immoral and represents bad science. It can also lead to general distrust in research amongst under-served groups. Designing and conducting clinical trials is a complex task, and all involved agree that investigators need adequate training to perform their duties. Despite this, there is no formal training on inclusivity in clinical trials available globally.