Lesion durability found during mandated percutaneous catheter
ablation after surgical cryo-ablation for treatment of
non-paroxysmal atrial fibrillation

J 2024

Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation

BULAVA, Alan, Ales MOKRACEK, Petr NĚMEC, Dan WICHTERLE, Pavel OSMANCIK et. al.

Základní údaje

Originální název

Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation

Autoři

BULAVA, Alan (203 Česká republika), Ales MOKRACEK (203 Česká republika), Petr NĚMEC (203 Česká republika, domácí), Dan WICHTERLE (203 Česká republika), Pavel OSMANCIK (203 Česká republika), Petr BUDERA (203 Česká republika), Petr KACER (203 Česká republika), Linda VETEŠKOVÁ (703 Slovensko, domácí), Tomas SKALA (203 Česká republika), Petr SANTAVY (203 Česká republika), Jan CHOVANCIK (203 Česká republika), Piotr BRANNY (203 Česká republika), Vitalii RIZOV (203 Česká republika), Miroslav KOLESAR (203 Česká republika), Iva SAFARIKOVA (203 Česká republika) a Marian RYBAR (203 Česká republika)

Vydání

Journal of Cardiothoracic Surgery, London, BMC, 2024, 1749-8090

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 1.600 v roce 2022

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1186/s13019-024-02889-3

UT WoS

001258112200009

Klíčová slova anglicky

Concomitant atrial fibrillation ablation; Staged hybrid ablation; CryoMaze procedure; Electrical conduction; Electrophysiological study; Gaps localization

Štítky

14110911, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 7. 2024 10:54, Mgr. Tereza Miškechová

Anotace

V originále

Objectives Current recommendations support surgical treatment of atrial fibrillation (AF) in patients indicated for cardiac surgery. These procedures are referred to as concomitant and may be carried out using radiofrequency energy or cryo-ablation. This study aimed to assess the electrophysiological findings in patients undergoing concomitant cryo-ablation. Methods Patients with non-paroxysmal AF undergoing coronary artery bypass grafting and/or valve repair/replacement were included in the trial if concomitant cryo-ablation was part of the treatment plan according to current guidelines. The patients reported in this study were assigned to undergo staged percutaneous radiofrequency catheter ablation (PRFCA), i.e., hybrid treatment, as a part of the SURHYB trial protocol. Results We analyzed 103 patients who underwent PRFCA 105 +/- 35 days after surgery. Left and right pulmonary veins (PVs) were found isolated in 65 (63.1%) and 63 (61.2%) patients, respectively. The LA posterior wall isolation and mitral isthmus conduction block were found in 38 (36.9%) and 18 (20.0%) patients, respectively. Electrical reconnections (gaps) in the left PVs were more often localized superiorly than inferiorly (57.9% vs. 26.3%, P = 0.005) and anteriorly than posteriorly (65.8% vs. 31.6%, P = 0.003). Gaps in the right PVs were more equally distributed anteroposteriorly but dominated in superior segments (72.5% vs. 40.0%, P = 0.003). There was a higher number of gaps on the roof line compared to the inferior line (131 (67.2%) vs. 67 (42.2%), P < 0.001). Compared to epicardial cryo-ablation, endocardial was more effective in creating PVs and LA posterior wall isolation (P < 0.05). Cryo-ablation using nitrous oxide (N20) or argon (Ar) gas as cooling agents was similarly effective (P = NS). Conclusions The effectiveness of surgical cryo-ablation in achieving transmural and durable lesions in the left atrium is surprisingly low. Gaps are located predominantly in the superior and anterior portions of the PVs and on the roof line. Endocardial cryo-ablation is more effective than epicardial ablation, irrespective of the cooling agent used.

Citovat

BULAVA, Alan, Ales MOKRACEK, Petr NĚMEC, Dan WICHTERLE, Pavel OSMANCIK, Petr BUDERA, Petr KACER, Linda VETEŠKOVÁ, Tomas SKALA, Petr SANTAVY, Jan CHOVANCIK, Piotr BRANNY, Vitalii RIZOV, Miroslav KOLESAR, Iva SAFARIKOVA a Marian RYBAR. Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation. Journal of Cardiothoracic Surgery. London: BMC, 2024, roč. 19, č. 1, s. 1-10. ISSN 1749-8090. Dostupné z: https://dx.doi.org/10.1186/s13019-024-02889-3.

@article{2418122,
   author = {Bulava, Alan and Mokracek, Ales and Němec, Petr and Wichterle, Dan and Osmancik, Pavel and Budera, Petr and Kacer, Petr and Vetešková, Linda and Skala, Tomas and Santavy, Petr and Chovancik, Jan and Branny, Piotr and Rizov, Vitalii and Kolesar, Miroslav and Safarikova, Iva and Rybar, Marian},
   article_location = {London},
   article_number = {1},
   doi = {http://dx.doi.org/10.1186/s13019-024-02889-3},
   keywords = {Concomitant atrial fibrillation ablation; Staged hybrid ablation; CryoMaze procedure; Electrical conduction; Electrophysiological study; Gaps localization},
   language = {eng},
   issn = {1749-8090},
   journal = {Journal of Cardiothoracic Surgery},
   title = {Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation},
   url = {https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-024-02889-3},
   volume = {19},
   year = {2024}
}

TY  - JOUR
ID  - 2418122
AU  - Bulava, Alan - Mokracek, Ales - Němec, Petr - Wichterle, Dan - Osmancik, Pavel - Budera, Petr - Kacer, Petr - Vetešková, Linda - Skala, Tomas - Santavy, Petr - Chovancik, Jan - Branny, Piotr - Rizov, Vitalii - Kolesar, Miroslav - Safarikova, Iva - Rybar, Marian
PY  - 2024
TI  - Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation
JF  - Journal of Cardiothoracic Surgery
VL  - 19
IS  - 1
SP  - 1-10
EP  - 1-10
PB  - BMC
SN  - 17498090
KW  - Concomitant atrial fibrillation ablation
KW  - Staged hybrid ablation
KW  - CryoMaze procedure
KW  - Electrical conduction
KW  - Electrophysiological study
KW  - Gaps localization
UR  - https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-024-02889-3
N2  - Objectives Current recommendations support surgical treatment of atrial fibrillation (AF) in patients indicated for cardiac surgery. These procedures are referred to as concomitant and may be carried out using radiofrequency energy or cryo-ablation. This study aimed to assess the electrophysiological findings in patients undergoing concomitant cryo-ablation. Methods Patients with non-paroxysmal AF undergoing coronary artery bypass grafting and/or valve repair/replacement were included in the trial if concomitant cryo-ablation was part of the treatment plan according to current guidelines. The patients reported in this study were assigned to undergo staged percutaneous radiofrequency catheter ablation (PRFCA), i.e., hybrid treatment, as a part of the SURHYB trial protocol. Results We analyzed 103 patients who underwent PRFCA 105 +/- 35 days after surgery. Left and right pulmonary veins (PVs) were found isolated in 65 (63.1%) and 63 (61.2%) patients, respectively. The LA posterior wall isolation and mitral isthmus conduction block were found in 38 (36.9%) and 18 (20.0%) patients, respectively. Electrical reconnections (gaps) in the left PVs were more often localized superiorly than inferiorly (57.9% vs. 26.3%, P = 0.005) and anteriorly than posteriorly (65.8% vs. 31.6%, P = 0.003). Gaps in the right PVs were more equally distributed anteroposteriorly but dominated in superior segments (72.5% vs. 40.0%, P = 0.003). There was a higher number of gaps on the roof line compared to the inferior line (131 (67.2%) vs. 67 (42.2%), P < 0.001). Compared to epicardial cryo-ablation, endocardial was more effective in creating PVs and LA posterior wall isolation (P < 0.05). Cryo-ablation using nitrous oxide (N20) or argon (Ar) gas as cooling agents was similarly effective (P = NS). Conclusions The effectiveness of surgical cryo-ablation in achieving transmural and durable lesions in the left atrium is surprisingly low. Gaps are located predominantly in the superior and anterior portions of the PVs and on the roof line. Endocardial cryo-ablation is more effective than epicardial ablation, irrespective of the cooling agent used.
ER  -

BULAVA, Alan, Ales MOKRACEK, Petr NĚMEC, Dan WICHTERLE, Pavel OSMANCIK, Petr BUDERA, Petr KACER, Linda VETEŠKOVÁ, Tomas SKALA, Petr SANTAVY, Jan CHOVANCIK, Piotr BRANNY, Vitalii RIZOV, Miroslav KOLESAR, Iva SAFARIKOVA a Marian RYBAR. Lesion durability found during mandated percutaneous catheter ablation after surgical cryo-ablation for treatment of non-paroxysmal atrial fibrillation. \textit{Journal of Cardiothoracic Surgery}. London: BMC, 2024, roč.~19, č.~1, s.~1-10. ISSN~1749-8090. Dostupné z: https://dx.doi.org/10.1186/s13019-024-02889-3.

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