a 2024

Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

ŠTRUBLOVÁ, Lucie, Tomáš KEPÁK, Kateřina KEPÁKOVÁ, Marta HOLÍKOVÁ, Filip ZLÁMAL et. al.

Základní údaje

Originální název

Socioeconomic status and adiposity in childhood cancer survivors: A cross-sectional retrospective study

Autoři

ŠTRUBLOVÁ, Lucie (203 Česká republika, garant, domácí), Tomáš KEPÁK (203 Česká republika), Kateřina KEPÁKOVÁ (203 Česká republika), Marta HOLÍKOVÁ (203 Česká republika), Filip ZLÁMAL (203 Česká republika), Daniela KURUCZOVÁ (703 Slovensko), Jaroslav ŠTĚRBA (203 Česká republika) a Julie BIENERTOVÁ-VAŠKŮ (203 Česká republika)

Vydání

3rd International Symposium on Late Complications after Childhood Cancer (ISLCCC) 2024, 2024

Další údaje

Jazyk

angličtina

Typ výsledku

Konferenční abstrakt

Obor

30304 Public and environmental health

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

late effects of childhood cancer unemployment adiposity socioeconomic status cancer survivorship
Změněno: 14. 7. 2024 11:09, Mgr. Lucie Štrublová

Anotace

V originále

Background/Purpose: This is a retrospective cross-sectional study examining the association between unemployment, cancer type, treatment and total body fat percentage of childhood cancer survivors recruited at St. Anne’s University Hospital in Brno, Czech Republic. Methods: A total of 55 survivors aged 18-49 who were in remission of cancer and fulfilled the criteria for body composition measurements by the BIA and completed questionnaires investigating their socioeconomic status, employment status, and history. Results: There was a significant relationship between the employment status and central nervous system-directed treatment ( χ2(1)=7.53, p=0.006, Cramér’s V=0.38) and between the type of cancer and employment status (χ2(3)=7.83, p=0.049, Cramér’s V=0.38), the highest unemployment rate was recorded for brain and spine survivors (72.7%) compared to survivors with other diagnosis (35.7%) (uLR(1)=4.91, p=0.027; OR=4.80, 95% CI:1.10-20.86, p=0.036); these survivors did not have a significantly different body fat percentage compared to survivors with other diagnoses (t(53)=1.29, p=0.202, Cohen’s d=0.41) Interestingly, the survivors reporting having a partner also had a significantly higher percentage of body fat (t(53)=2.90, p=0.005, Cohen’s d=0.81). A linear regression model was used to model the percentage of body fat in relation to a set of selected variables and the we observed a significant effect of sex (female vs male: b=6.37, 95% CI: 1.82- 10.93, p=0.007), partnership status (yes vs no: b=5.65, 95% CI: 0.67-10.62, p=0.027) and category of diagnosis (Brain and spinal column tumors vs Other solid tumors: b=12.40, 95% CI: 0.59-24.21, p=0.040 ; Brain and spinal column tumors vs Lymphoma: b=14.02, 95% CI: 2.06-25.97, p=0.023). Conclusion: Employment status and risk of adiposity in childhood cancer survivors depends on the type of treatment and diagnosis group, which may significantly impact their lifestyle and overall quality of life after treatment.

Návaznosti

MUNI/A/1391/2021, interní kód MU
Název: Molekulární, buněčná, tkáňová a systémová patofyziologie vybraných komplexních nemocí (Akronym: KOMPLEX_PF)
Investor: Masarykova univerzita, Molekulární, buněčná, tkáňová a systémová patofyziologie vybraných komplexních nemocí