High frequency oscillations in human memory and cognition: a
neurophysiological substrate of engrams?

J 2024

High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?

KUCEWICZ, Michal T, Jan CIMBÁLNÍK, Jesus S S GARCIA, Milan BRÁZDIL, Gregory A WORRELL et. al.

Základní údaje

Originální název

High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?

Autoři

KUCEWICZ, Michal T, Jan CIMBÁLNÍK, Jesus S S GARCIA, Milan BRÁZDIL a Gregory A WORRELL

Vydání

Brain, OXFORD, OXFORD UNIV PRESS, 2024, 0006-8950

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30210 Clinical neurology

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 14.500 v roce 2022

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1093/brain/awae159

UT WoS

999

Klíčová slova anglicky

network oscillations; intracranial EEG; local field potential; cognition; sharp-wave ripples; memory consolidation

Štítky

14110127, podil

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 15. 7. 2024 12:17, Mgr. Tereza Miškechová

Anotace

V originále

Despite advances in understanding the cellular and molecular processes underlying memory and cognition, and recent successful modulation of cognitive performance in brain disorders, the neurophysiological mechanisms remain underexplored. High frequency oscillations beyond the classic electroencephalogram spectrum have emerged as a potential neural correlate of fundamental cognitive processes. High frequency oscillations are detected in the human mesial temporal lobe and neocortical intracranial recordings spanning gamma/epsilon (60-150 Hz), ripple (80-250 Hz) and higher frequency ranges. Separate from other non-oscillatory activities, these brief electrophysiological oscillations of distinct duration, frequency and amplitude are thought to be generated by coordinated spiking of neuronal ensembles within volumes as small as a single cortical column. Although the exact origins, mechanisms, and physiological roles in health and disease remain elusive, they have been associated with human memory consolidation and cognitive processing. Recent studies suggest their involvement in encoding and recall of episodic memory with a possible role in the formation and reactivation of memory traces. High frequency oscillations are detected during encoding, throughout maintenance, and right before recall of remembered items, meeting a basic definition for an engram activity. The temporal coordination of high frequency oscillations reactivated across cortical and subcortical neural networks is ideally suited for integrating multimodal memory representations, which can be replayed and consolidated during states of wakefulness and sleep. High frequency oscillations have been shown to reflect coordinated bursts of neuronal assembly firing and offer a promising substrate for tracking and modulation of the hypothetical electrophysiological engram.

Citovat

KUCEWICZ, Michal T, Jan CIMBÁLNÍK, Jesus S S GARCIA, Milan BRÁZDIL a Gregory A WORRELL. High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams? Brain. OXFORD: OXFORD UNIV PRESS, 2024. ISSN 0006-8950. Dostupné z: https://dx.doi.org/10.1093/brain/awae159.

@article{2418603,
   author = {Kucewicz, Michal T and Cimbálník, Jan and Garcia, Jesus S S and Brázdil, Milan and Worrell, Gregory A},
   article_location = {OXFORD},
   doi = {http://dx.doi.org/10.1093/brain/awae159},
   keywords = {network oscillations; intracranial EEG; local field potential; cognition; sharp-wave ripples; memory consolidation},
   language = {eng},
   issn = {0006-8950},
   journal = {Brain},
   title = {High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?},
   url = {https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awae159/7672954?login=true},
   year = {2024}
}

TY  - JOUR
ID  - 2418603
AU  - Kucewicz, Michal T - Cimbálník, Jan - Garcia, Jesus S S - Brázdil, Milan - Worrell, Gregory A
PY  - 2024
TI  - High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams?
JF  - Brain
PB  - OXFORD UNIV PRESS
SN  - 00068950
KW  - network oscillations
KW  - intracranial EEG
KW  - local field potential
KW  - cognition
KW  - sharp-wave ripples
KW  - memory consolidation
UR  - https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awae159/7672954?login=true
N2  - Despite advances in understanding the cellular and molecular processes underlying memory and cognition, and recent successful modulation of cognitive performance in brain disorders, the neurophysiological mechanisms remain underexplored. High frequency oscillations beyond the classic electroencephalogram spectrum have emerged as a potential neural correlate of fundamental cognitive processes. High frequency oscillations are detected in the human mesial temporal lobe and neocortical intracranial recordings spanning gamma/epsilon (60-150 Hz), ripple (80-250 Hz) and higher frequency ranges. Separate from other non-oscillatory activities, these brief electrophysiological oscillations of distinct duration, frequency and amplitude are thought to be generated by coordinated spiking of neuronal ensembles within volumes as small as a single cortical column. Although the exact origins, mechanisms, and physiological roles in health and disease remain elusive, they have been associated with human memory consolidation and cognitive processing. Recent studies suggest their involvement in encoding and recall of episodic memory with a possible role in the formation and reactivation of memory traces. High frequency oscillations are detected during encoding, throughout maintenance, and right before recall of remembered items, meeting a basic definition for an engram activity. The temporal coordination of high frequency oscillations reactivated across cortical and subcortical neural networks is ideally suited for integrating multimodal memory representations, which can be replayed and consolidated during states of wakefulness and sleep. High frequency oscillations have been shown to reflect coordinated bursts of neuronal assembly firing and offer a promising substrate for tracking and modulation of the hypothetical electrophysiological engram.
ER  -

KUCEWICZ, Michal T, Jan CIMBÁLNÍK, Jesus S S GARCIA, Milan BRÁZDIL a Gregory A WORRELL. High frequency oscillations in human memory and cognition: a neurophysiological substrate of engrams? \textit{Brain}. OXFORD: OXFORD UNIV PRESS, 2024. ISSN~0006-8950. Dostupné z: https://dx.doi.org/10.1093/brain/awae159.

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