J 2024

Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption

SAHA, Utsa, Puja KUMARI, Aishee GHOSH, Adrija SINHA, Snehasmita JENA et. al.

Základní údaje

Originální název

Detrimental consequences of micropolymers associated plasticizers on endocrinal disruption

Autoři

SAHA, Utsa, Puja KUMARI (356 Indie, garant, domácí), Aishee GHOSH, Adrija SINHA, Snehasmita JENA, Apoorv KIRTI, Abha GUPTA, Anmol CHOUDHURY, Faizan Zareen SIMNANI, Aditya NANDI, Rudra Narayan SAHOO, Shalini KUMARI, Richa MISHRA, Nagendra Kumar KAUSHIK, Deobrat SINGH, Mrutyunjay SUAR a Suresh K. VERMA

Vydání

Materials Today Bio, AMSTERDAM, Elsevier, 2024, 2590-0064

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30404 Biomaterials

Stát vydavatele

Nizozemské království

Utajení

není předmětem státního či obchodního tajemství

Odkazy

Impakt faktor

Impact factor: 8.200 v roce 2022

Organizační jednotka

Přírodovědecká fakulta

UT WoS

001260174300001

Klíčová slova anglicky

Microplastic; Nanoplastic; Plasticizers; Hormones; Endocrine disrupting chemical; Hypothalamus -pituitary axis

Příznaky

Mezinárodní význam, Recenzováno
Změněno: 5. 8. 2024 08:34, Mgr. Michaela Hylsová, Ph.D.

Anotace

V originále

The prevalence of polymer usage in everyday activities has emerged as a detriment to both human life and the environment. A large number of studies describe severe impacts of micropolymers (MP) and nanopolymers (NP) on various organ systems, including the endocrine system. Additionally, plasticizers utilized as additives have been identified as endocrine-disrupting chemicals (EDCs). MP/NP, along with associated plasticizers, affect principal signalling pathways of endocrine glands such as the pituitary, thyroid, adrenal, and gonads, thereby disrupting hormone function and metabolic processes crucial for maintaining homeostasis, fertility, neural development, and fetal growth. This review delves into the sources, distribution, and effects of micropolymers, nanopolymers, and associated plasticizers acting as EDCs. Furthermore, it provides a detailed review of the mechanisms underlying endocrine disruption in relation to different types of MP/NP.