Aortic valve performance after remodelling versus
reimplantation in a propensity-matched comparison

J 2024

Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison

GOFUS, Jan, Jan VOJACEK, Mikita KARALKO, Pavel ZACEK, Adrian KOLESAR et. al.

Základní údaje

Originální název

Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison

Autoři

GOFUS, Jan (203 Česká republika), Jan VOJACEK (203 Česká republika), Mikita KARALKO, Pavel ZACEK (203 Česká republika), Adrian KOLESAR (203 Česká republika), Tomas TOPORCER (203 Česká republika), Martin URBAN (203 Česká republika), Filip GLAC (203 Česká republika), Stepan CERNY (203 Česká republika), Pavel HOMOLA (203 Česká republika), Jaroslav HLUBOCKY (203 Česká republika), Andrey SLAUTIN, Petr FILA (203 Česká republika, domácí), Daniela ŽÁKOVÁ (203 Česká republika, domácí), Jan ŠTĚRBA (203 Česká republika, domácí), Hiwad RASHID, Arnaud VAN LINDEN a Tomas HOLUBEC (203 Česká republika)

Vydání

EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, CARY, OXFORD UNIV PRESS INC, 2024, 1010-7940

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.400 v roce 2022

Organizační jednotka

Lékařská fakulta

DOI

http://dx.doi.org/10.1093/ejcts/ezae234

UT WoS

001284515800001

Klíčová slova anglicky

Aortic valve repair; Valve-sparing root replacement; Aortic root aneurysm; Aortic regurgitation; Propensity-score matching

Štítky

14110911, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 19. 8. 2024 08:28, Mgr. Tereza Miškechová

Anotace

V originále

OBJECTIVES: Both aortic root remodelling and aortic valve (AV) reimplantation have been used for valve-sparing root replacement in patients with aortic root aneurysm with or without aortic regurgitation. There is no clear evidence to support one technique over the another. This study aimed to compare remodelling with basal ring annuloplasty versus reimplantation on a multicentre level with the use of propensity-score matching. METHODS: This was a retrospective international multicentre study of patients undergoing remodelling or reimplantation between 2010 and 2021. Twenty-three preoperative covariates (including root dimensions and valve characteristics) were used for propensity-score matching. Perioperative outcomes were analysed along with longer-term freedom from AV reoperation/reintervention and other major valve-related events. RESULTS: Throughout the study period, 297 patients underwent remodelling and 281 had reimplantation. Using propensity-score matching, 112 pairs were selected and further compared. We did not find a statistically significant difference in perioperative outcomes between the matched groups. Patients after remodelling had significantly higher reintervention risk than after reimplantation over the median follow-up of 6 years (P = 0.016). The remodelling technique (P = 0.02), need for decalcification (P = 0.03) and degree of immediate postoperative AV regurgitation (P < 0.001) were defined as independent risk factors for later AV reintervention. After exclusion of patients with worse than mild AV regurgitation immediately after repair, both techniques functioned comparably (P = 0.089). CONCLUSIONS: AV reimplantation was associated with better valve function in longer-term postoperatively than remodelling. If optimal immediate repair outcome was achieved, both techniques provided comparable AV function.

Citovat

GOFUS, Jan, Jan VOJACEK, Mikita KARALKO, Pavel ZACEK, Adrian KOLESAR, Tomas TOPORCER, Martin URBAN, Filip GLAC, Stepan CERNY, Pavel HOMOLA, Jaroslav HLUBOCKY, Andrey SLAUTIN, Petr FILA, Daniela ŽÁKOVÁ, Jan ŠTĚRBA, Hiwad RASHID, Arnaud VAN LINDEN a Tomas HOLUBEC. Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY. CARY: OXFORD UNIV PRESS INC, 2024, roč. 66, č. 2, s. 1-9. ISSN 1010-7940. Dostupné z: https://dx.doi.org/10.1093/ejcts/ezae234.

@article{2423719,
   author = {Gofus, Jan and Vojacek, Jan and Karalko, Mikita and Zacek, Pavel and Kolesar, Adrian and Toporcer, Tomas and Urban, Martin and Glac, Filip and Cerny, Stepan and Homola, Pavel and Hlubocky, Jaroslav and Slautin, Andrey and Fila, Petr and Žáková, Daniela and Štěrba, Jan and Rashid, Hiwad and Van Linden, Arnaud and Holubec, Tomas},
   article_location = {CARY},
   article_number = {2},
   doi = {http://dx.doi.org/10.1093/ejcts/ezae234},
   keywords = {Aortic valve repair; Valve-sparing root replacement; Aortic root aneurysm; Aortic regurgitation; Propensity-score matching},
   language = {eng},
   issn = {1010-7940},
   journal = {EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY},
   title = {Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison},
   url = {https://academic.oup.com/ejcts/article/66/2/ezae234/7727652?login=true},
   volume = {66},
   year = {2024}
}

TY  - JOUR
ID  - 2423719
AU  - Gofus, Jan - Vojacek, Jan - Karalko, Mikita - Zacek, Pavel - Kolesar, Adrian - Toporcer, Tomas - Urban, Martin - Glac, Filip - Cerny, Stepan - Homola, Pavel - Hlubocky, Jaroslav - Slautin, Andrey - Fila, Petr - Žáková, Daniela - Štěrba, Jan - Rashid, Hiwad - Van Linden, Arnaud - Holubec, Tomas
PY  - 2024
TI  - Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison
JF  - EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
VL  - 66
IS  - 2
SP  - 1-9
EP  - 1-9
PB  - OXFORD UNIV PRESS INC
SN  - 10107940
KW  - Aortic valve repair
KW  - Valve-sparing root replacement
KW  - Aortic root aneurysm
KW  - Aortic regurgitation
KW  - Propensity-score matching
UR  - https://academic.oup.com/ejcts/article/66/2/ezae234/7727652?login=true
N2  - OBJECTIVES: Both aortic root remodelling and aortic valve (AV) reimplantation have been used for valve-sparing root replacement in patients with aortic root aneurysm with or without aortic regurgitation. There is no clear evidence to support one technique over the another. This study aimed to compare remodelling with basal ring annuloplasty versus reimplantation on a multicentre level with the use of propensity-score matching. METHODS: This was a retrospective international multicentre study of patients undergoing remodelling or reimplantation between 2010 and 2021. Twenty-three preoperative covariates (including root dimensions and valve characteristics) were used for propensity-score matching. Perioperative outcomes were analysed along with longer-term freedom from AV reoperation/reintervention and other major valve-related events. RESULTS: Throughout the study period, 297 patients underwent remodelling and 281 had reimplantation. Using propensity-score matching, 112 pairs were selected and further compared. We did not find a statistically significant difference in perioperative outcomes between the matched groups. Patients after remodelling had significantly higher reintervention risk than after reimplantation over the median follow-up of 6 years (P = 0.016). The remodelling technique (P = 0.02), need for decalcification (P = 0.03) and degree of immediate postoperative AV regurgitation (P < 0.001) were defined as independent risk factors for later AV reintervention. After exclusion of patients with worse than mild AV regurgitation immediately after repair, both techniques functioned comparably (P = 0.089). CONCLUSIONS: AV reimplantation was associated with better valve function in longer-term postoperatively than remodelling. If optimal immediate repair outcome was achieved, both techniques provided comparable AV function.
ER  -

GOFUS, Jan, Jan VOJACEK, Mikita KARALKO, Pavel ZACEK, Adrian KOLESAR, Tomas TOPORCER, Martin URBAN, Filip GLAC, Stepan CERNY, Pavel HOMOLA, Jaroslav HLUBOCKY, Andrey SLAUTIN, Petr FILA, Daniela ŽÁKOVÁ, Jan ŠTĚRBA, Hiwad RASHID, Arnaud VAN LINDEN a Tomas HOLUBEC. Aortic valve performance after remodelling versus reimplantation in a propensity-matched comparison. \textit{EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY}. CARY: OXFORD UNIV PRESS INC, 2024, roč.~66, č.~2, s.~1-9. ISSN~1010-7940. Dostupné z: https://dx.doi.org/10.1093/ejcts/ezae234.

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