Luminescent photon-upconversion nanoparticles with advanced
functionalization for smart sensing and imaging

J 2024

Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging

SKLÁDAL, Petr and Zdeněk FARKA

Basic information

Original name

Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging

Authors

SKLÁDAL, Petr and Zdeněk FARKA

Edition

Microchimica Acta, Springer-Verlag GmbH Austria, 2024, 0026-3672

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10406 Analytical chemistry

Country of publisher

Austria

Confidentiality degree

is not subject to a state or trade secret

References:

URL

Impact factor

Impact factor: 5.300

Marked to be transferred to RIV

Yes

RIV identification code

RIV/00216224:14310/24:00136927

Organization unit

Faculty of Science

Keywords in English

Fluorescent dyes; Resonance energy transfer; Bioconjugates; Intracellular biosensor; Nanosensor

Abstract

In the original language

Photon-upconversion nanoparticles (UCNP) have already been established as labels for affinity assays in analog and digital formats. Here, advanced, or smart, systems based on UCNPs coated with active shells, fluorescent dyes, and metal and semiconductor nanoparticles participating in energy transfer reactions are reviewed. In addition, switching elements can be embedded in such assemblies and provide temporal and spatial control of action, which is important for intracellular imaging and monitoring activities. Demonstration and critical comments on representative approaches demonstrating the progress in the use of such UCNPs in bioanalytical assays, imaging, and monitoring of target molecules in cells are reported, including particular examples in the field of cancer theranostics.

Links

CZ.02.01.01/00/22_008/0004596, interní kód MU

Name: Sensory a detektory pro budoucí informační společnost

Investor: Ministry of Education, Youth and Sports of the CR, Sensors and Detectors for Information Society, Priority 1 - Research and development

EH22_008/0004596, research and development project

Name: Senzory a detektory pro informační společnost budoucnosti

GA21-03156S, research and development project

Name: Foton-upkonverzní značky pro mikrofluidní jednomolekulové imunostanovení proteinových biomarkerů

Investor: Czech Science Foundation

Cite

SKLÁDAL, Petr and Zdeněk FARKA. Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging. Microchimica Acta. Springer-Verlag GmbH Austria, 2024, vol. 191, No 9, p. 1-15. ISSN 0026-3672. Available from: https://doi.org/10.1007/s00604-024-06615-7.

@article{2425607,
   author = {Skládal, Petr and Farka, Zdeněk},
   article_number = {9},
   doi = {https://doi.org/10.1007/s00604-024-06615-7},
   keywords = {Fluorescent dyes; Resonance energy transfer; Bioconjugates; Intracellular biosensor; Nanosensor},
   language = {eng},
   issn = {0026-3672},
   journal = {Microchimica Acta},
   title = {Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging},
   url = {https://link.springer.com/article/10.1007/s00604-024-06615-7},
   volume = {191},
   year = {2024}
}

TY  - JOUR
ID  - 2425607
AU  - Skládal, Petr - Farka, Zdeněk
PY  - 2024
TI  - Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging
JF  - Microchimica Acta
VL  - 191
IS  - 9
SP  - 1-15
EP  - 1-15
PB  - Springer-Verlag GmbH Austria
SN  - 00263672
KW  - Fluorescent dyes
KW  - Resonance energy transfer
KW  - Bioconjugates
KW  - Intracellular biosensor
KW  - Nanosensor
UR  - https://link.springer.com/article/10.1007/s00604-024-06615-7
N2  - Photon-upconversion nanoparticles (UCNP) have already been established as labels for affinity assays in analog and digital formats. Here, advanced, or smart, systems based on UCNPs coated with active shells, fluorescent dyes, and metal and semiconductor nanoparticles participating in energy transfer reactions are reviewed. In addition, switching elements can be embedded in such assemblies and provide temporal and spatial control of action, which is important for intracellular imaging and monitoring activities. Demonstration and critical comments on representative approaches demonstrating the progress in the use of such UCNPs in bioanalytical assays, imaging, and monitoring of target molecules in cells are reported, including particular examples in the field of cancer theranostics.
ER  -

SKLÁDAL, Petr and Zdeněk FARKA. Luminescent photon-upconversion nanoparticles with advanced functionalization for smart sensing and imaging. \textit{Microchimica Acta}. Springer-Verlag GmbH Austria, 2024, vol.~191, No~9, p.~1-15. ISSN~0026-3672. Available from: https://doi.org/10.1007/s00604-024-06615-7.

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