Další formáty:
BibTeX
LaTeX
RIS
@article{2430478, author = {Lázňovský, Jakub and Kavková, Michaela and Reis, Alice Helena and RobovskaandHavelkova, Pavla and Agostini Maia, Lorena and Křivánek, Jan and Zikmund, Tomas and Kaiser, Jozef and Buchtová, Marcela and Harnoš, Jakub}, article_location = {OXFORD}, article_number = {JUNE}, doi = {http://dx.doi.org/10.1093/gigascience/giae037}, keywords = {Xenopus laevis; development; vertebrates; micro-computed tomography; morphological changes}, language = {eng}, issn = {2047-217X}, journal = {GigaScience}, title = {Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging}, url = {https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae037/7714386?login=true}, volume = {13}, year = {2024} }
TY - JOUR ID - 2430478 AU - Lázňovský, Jakub - Kavková, Michaela - Reis, Alice Helena - Robovska-Havelkova, Pavla - Agostini Maia, Lorena - Křivánek, Jan - Zikmund, Tomas - Kaiser, Jozef - Buchtová, Marcela - Harnoš, Jakub PY - 2024 TI - Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging JF - GigaScience VL - 13 IS - JUNE SP - 1-16 EP - 1-16 PB - Oxford University Press SN - 2047217X KW - Xenopus laevis KW - development KW - vertebrates KW - micro-computed tomography KW - morphological changes UR - https://academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae037/7714386?login=true N2 - Background Xenopus laevis, the African clawed frog, is a versatile vertebrate model organism in various biological disciplines, prominently in developmental biology to study body plan reorganization during metamorphosis. However, a notable gap exists in the availability of comprehensive datasets encompassing Xenopus' late developmental stages.Findings This study utilized micro-computed tomography (micro-CT), a noninvasive 3-dimensional (3D) imaging technique with micrometer-scale resolution, to explore the developmental dynamics and morphological changes in Xenopus laevis. Our approach involved generating high-resolution images and computed 3D models of developing Xenopus specimens, spanning from premetamorphosis tadpoles to fully mature adults. This dataset enhances our understanding of vertebrate development and supports various analyses. We conducted a careful examination, analyzing body size, shape, and morphological features, focusing on skeletogenesis, teeth, and organs like the brain and gut at different stages. Our analysis yielded valuable insights into 3D morphological changes during Xenopus' development, documenting details previously unrecorded. These datasets hold the solid potential for further morphological and morphometric analyses, including segmentation of hard and soft tissues.Conclusions Our repository of micro-CT scans represents a significant resource that can enhance our understanding of Xenopus' development and the associated morphological changes in the future. The widespread utility of this amphibian species, coupled with the exceptional quality of our scans, which encompass a comprehensive series of developmental stages, opens up extensive opportunities for their broader research application. Moreover, these scans can be used in virtual reality, 3D printing, and educational contexts, further expanding their value and impact. ER -
LÁZŇOVSKÝ, Jakub, Michaela KAVKOVÁ, Alice Helena REIS, Pavla ROBOVSKA-HAVELKOVA, Lorena AGOSTINI MAIA, Jan KŘIVÁNEK, Tomas ZIKMUND, Jozef KAISER, Marcela BUCHTOVÁ a Jakub HARNOŠ. Unveiling vertebrate development dynamics in frog Xenopus laevis using micro-CT imaging. \textit{GigaScience}. OXFORD: Oxford University Press, 2024, roč.~13, JUNE, s.~1-16. ISSN~2047-217X. Dostupné z: https://dx.doi.org/10.1093/gigascience/giae037.
|