Centromere drive may propel the evolution of chromosome and
genome size in plants

J 2024

Centromere drive may propel the evolution of chromosome and genome size in plants

PLAČKOVÁ, Klára; Petr BUREŠ; Martin LYSÁK a František ZEDEK

Základní údaje

Originální název

Centromere drive may propel the evolution of chromosome and genome size in plants

Autoři

PLAČKOVÁ, Klára; Petr BUREŠ; Martin LYSÁK a František ZEDEK

Vydání

Annals of Botany, Oxford, Oxford University Press, 2024, 0305-7364

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

10611 Plant sciences, botany

Stát vydavatele

Velká Británie a Severní Irsko

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.600

Označené pro přenos do RIV

Ano

Kód RIV

RIV/00216224:14310/24:00137354

Organizační jednotka

Přírodovědecká fakulta

Klíčová slova anglicky

Angiosperms; asymmetric and symmetric meiosis; bryophytes; CENH3; centromere drive; chromosome size; ferns; genome size; gymnosperms; lycophytes; post-polyploid diploidization

Štítky

14314020, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 16. 4. 2025 09:49, Mgr. Eva Dubská

Anotace

V originále

Background: Genome size is influenced by natural selection and genetic drift acting on variations from polyploidy and repetitive DNA sequences. We hypothesized that centromere drive, where centromeres compete for inclusion in the functional gamete during meiosis, may also affect genome and chromosome size. This competition occurs in asymmetric meiosis, where only one of the four meiotic products becomes a gamete. If centromere drive influences chromosome size evolution, it may also impact post-polyploid diploidization, where a polyploid genome is restructured to function more like a diploid through chromosomal rearrangements, including fusions. We tested if plant lineages with asymmetric meiosis exhibit faster chromosome size evolution compared to those with only symmetric meiosis, which lack centromere drive as all four meiotic products become gametes. We also examined if positive selection on centromeric histone H3 (CENH3), a protein that can suppress centromere drive, is more frequent in these asymmetric lineages. Methods: We analysed plant groups with different meiotic modes: asymmetric in gymnosperms and angiosperms, and symmetric in bryophytes, lycophytes and ferns. We selected species based on available CENH3 gene sequences and chromosome size data. Using Ornstein-Uhlenbeck evolutionary models and phylogenetic regressions, we assessed the rates of chromosome size evolution and the frequency of positive selection on CENH3 in these clades. Results: Our analyses showed that clades with asymmetric meiosis have a higher frequency of positive selection on CENH3 and increased rates of chromosome size evolution compared to symmetric clades. Conclusions: Our findings support the hypothesis that centromere drive accelerates chromosome and genome size evolution, potentially also influencing the process of post-polyploid diploidization. We propose a model which in a single framework helps explain the stability of chromosome size in symmetric lineages (bryophytes, lycophytes and ferns) and its variability in asymmetric lineages (gymnosperms and angiosperms), providing a foundation for future research in plant genome evolution.

Návaznosti

EH22_008/0004581, projekt VaV

Název: Nové poznatky pro plodiny nové generace

GA20-15989S, projekt VaV

Název: Evoluce velikosti genomu - centromerický drajv v nové roli (Akronym: Centrogenomtah)

Investor: Grantová agentura ČR, Evolution of genome size - a new role for the centromere drive

MUNI/A/0977/2009, interní kód MU

Název: Moderní metody biochemického výzkumu

Investor: Masarykova univerzita, Moderní metody biochemického výzkumu, DO R. 2020_Kategorie A - Specifický výzkum - Studentské výzkumné projekty

Přiložené soubory

mcae149.pdf

Citovat

PLAČKOVÁ, Klára; Petr BUREŠ; Martin LYSÁK a František ZEDEK. Centromere drive may propel the evolution of chromosome and genome size in plants. Annals of Botany. Oxford: Oxford University Press, 2024, roč. 134, č. 6, s. 1067-1076. ISSN 0305-7364. Dostupné z: https://doi.org/10.1093/aob/mcae149.

@article{2444151,
   author = {Plačková, Klára and Bureš, Petr and Lysák, Martin and Zedek, František},
   article_location = {Oxford},
   article_number = {6},
   doi = {https://doi.org/10.1093/aob/mcae149},
   keywords = {Angiosperms; asymmetric and symmetric meiosis; bryophytes; CENH3; centromere drive; chromosome size; ferns; genome size; gymnosperms; lycophytes; post-polyploid diploidization},
   language = {eng},
   issn = {0305-7364},
   journal = {Annals of Botany},
   title = {Centromere drive may propel the evolution of chromosome and genome size in plants},
   url = {https://doi.org/10.1093/aob/mcae149},
   volume = {134},
   year = {2024}
}

TY  - JOUR
ID  - 2444151
AU  - Plačková, Klára - Bureš, Petr - Lysák, Martin - Zedek, František
PY  - 2024
TI  - Centromere drive may propel the evolution of chromosome and genome size in plants
JF  - Annals of Botany
VL  - 134
IS  - 6
SP  - 1067-1076
EP  - 1067-1076
PB  - Oxford University Press
SN  - 03057364
KW  - Angiosperms
KW  - asymmetric and symmetric meiosis
KW  - bryophytes
KW  - CENH3
KW  - centromere drive
KW  - chromosome size
KW  - ferns
KW  - genome size
KW  - gymnosperms
KW  - lycophytes
KW  - post-polyploid diploidization
UR  - https://doi.org/10.1093/aob/mcae149
N2  - Background: Genome size is influenced by natural selection and genetic drift acting on variations from polyploidy and repetitive DNA sequences. We hypothesized that centromere drive, where centromeres compete for inclusion in the functional gamete during meiosis, may also affect genome and chromosome size. This competition occurs in asymmetric meiosis, where only one of the four meiotic products becomes a gamete. If centromere drive influences chromosome size evolution, it may also impact post-polyploid diploidization, where a polyploid genome is restructured to function more like a diploid through chromosomal rearrangements, including fusions. We tested if plant lineages with asymmetric meiosis exhibit faster chromosome size evolution compared to those with only symmetric meiosis, which lack centromere drive as all four meiotic products become gametes. We also examined if positive selection on centromeric histone H3 (CENH3), a protein that can suppress centromere drive, is more frequent in these asymmetric lineages. Methods: We analysed plant groups with different meiotic modes: asymmetric in gymnosperms and angiosperms, and symmetric in bryophytes, lycophytes and ferns. We selected species based on available CENH3 gene sequences and chromosome size data. Using Ornstein-Uhlenbeck evolutionary models and phylogenetic regressions, we assessed the rates of chromosome size evolution and the frequency of positive selection on CENH3 in these clades. Results: Our analyses showed that clades with asymmetric meiosis have a higher frequency of positive selection on CENH3 and increased rates of chromosome size evolution compared to symmetric clades. Conclusions: Our findings support the hypothesis that centromere drive accelerates chromosome and genome size evolution, potentially also influencing the process of post-polyploid diploidization. We propose a model which in a single framework helps explain the stability of chromosome size in symmetric lineages (bryophytes, lycophytes and ferns) and its variability in asymmetric lineages (gymnosperms and angiosperms), providing a foundation for future research in plant genome evolution.
ER  -

PLAČKOVÁ, Klára; Petr BUREŠ; Martin LYSÁK a František ZEDEK. Centromere drive may propel the evolution of chromosome and genome size in plants. \textit{Annals of Botany}. Oxford: Oxford University Press, 2024, roč.~134, č.~6, s.~1067-1076. ISSN~0305-7364. Dostupné z: https://doi.org/10.1093/aob/mcae149.

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