2025
Vitamin B12 intake during pregnancy linked to child speech development and intelligence quotient
HREŽOVÁ, Eliška; Gabriela KŠIŇANOVÁ; Tomáš PRUŠA; Lenka ANDRÝSKOVÁ; Hynek PIKHART et al.Základní údaje
Originální název
Vitamin B12 intake during pregnancy linked to child speech development and intelligence quotient
Autoři
Vydání
JOURNAL OF PUBLIC HEALTH, ENGLAND, OXFORD UNIV PRESS, 2025, 1741-3842
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
30304 Public and environmental health
Stát vydavatele
Velká Británie a Severní Irsko
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 3.100 v roce 2024
Označené pro přenos do RIV
Ano
Kód RIV
RIV/00216224:14310/25:00140431
Organizační jednotka
Přírodovědecká fakulta
UT WoS
EID Scopus
Klíčová slova anglicky
children; epidemiology; food and nutrition
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 23. 6. 2026 11:17, Mgr. Michaela Hylsová, Ph.D.
Anotace
V originále
Background Nutrient deficiencies during pregnancy may affect offspring development. We aim to examine the association between prenatal vitamin B12 intake and children’s cognitive development. Methods A total of 5151 mother–child pairs from the Czech part of ELSPAC study were included in the analysis. Dietary information was obtained during pregnancy using food frequency questionnaire. Parents reported on their child’s speech and language development at 18 months, 3, 5 and 7 years. Intelligence quotient (IQ) was measured at 8 years in subcohort of 854 children. Results Children of mothers with higher vitamin B12 intake demonstrated higher scores in language (B = 0.20, 95% CI 0.06, 0.34) and talking and understanding (B = 2.39, 95% CI 0.97, 3.80) in a fully adjusted model at 18 months. Additionally, they were more likely to get maximum points in the intelligibility test at age 3 (OR = 1.05, 95% CI 1.01, 1.09) in unadjusted model, however, not in fully adjusted model. We found a positive effect of higher vitamin B12 intake on verbal IQ (B = 1.08, 95% CI 0.09, 2.08). Conclusions We identified consistent associations between prenatal vitamin B12 intake and children’s cognitive development. The results suggest that inadequate vitamin B12 during pregnancy may negatively affect children’s cognitive development, particularly in speech and language.
Návaznosti
| LX22NPO5101, projekt VaV |
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| 857487, interní kód MU |
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| 857560, interní kód MU (Kód CEP: EF17_043/0009632) |
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| 90269, velká výzkumná infrastruktura |
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