Chapter 16 - Interactions among the three protein states

C 2024

Chapter 16 - Interactions among the three protein states

KADEŘÁVEK, Pavel, Karel KUBÍČEK a Lukáš ŽÍDEK

Základní údaje

Originální název

Chapter 16 - Interactions among the three protein states

Autoři

KADEŘÁVEK, Pavel (203 Česká republika, domácí), Karel KUBÍČEK (203 Česká republika, domácí) a Lukáš ŽÍDEK (203 Česká republika, garant, domácí)

Vydání

525 B ST, STE 1900, SAN DIEGO, CA 92101- The Three Functional States of Proteins. Structured, Intrinsically Disordered, and Phase Separated, od s. 297-313, 17 s. The Three Functional States of Proteins Structured, Intrinsically Disordered, and Phase Separated, 2024

Nakladatel

Academic Press

Další údaje

Jazyk

angličtina

Typ výsledku

Kapitola resp. kapitoly v odborné knize

Obor

10608 Biochemistry and molecular biology

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Forma vydání

tištěná verze "print"

Odkazy

URL

Organizační jednotka

Středoevropský technologický institut

ISBN

978-0-443-21809-5

DOI

http://dx.doi.org/10.1016/C2023-0-00063-2

Klíčová slova anglicky

structured proteins; intrinsically disordered proteins; phase separated proteins; cellular life; health; disease

Štítky

rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 12. 3. 2025 13:39, Mgr. Eva Dubská

Anotace

V originále

Interactions between the three states of proteins (structured, intrinsically disordered, and phase separated) can be probed by a variety of experimental methods. First, we review fundamental physical forces determining structural features and intermolecular interactions of all three states of proteins. We classify individual contributions of the interactions, comment on their theoretical treatment, stress the importance of water as a solvent, and discuss the hierarchy of protein structures. Then we briefly mention methods of structure determination at the atomic resolution and describe in more detail selected methods probing specific features of intra- and intermolecular protein interactions. The selection includes various methods of nuclear magnetic resonance spectroscopy (including analysis of chemical shifts, relaxation effects, and measurements of translational diffusion and proton exchange) and methods reflecting hydrodynamic behavior, namely, analytical ultracentrifugation and small-angle X-ray scattering. The text does not have an ambition to provide actual protocols or a complete list of applications but tries to comment on the use of the methods for the three states of proteins.

Návaznosti

GA20-12669S, projekt VaV

Název: Interakce určující fyziologické funkce proteinu Microtubule Associated Protein 2c s atomovým rozlišením

Investor: Grantová agentura ČR, Interactions defining physiological functions of Microtubule Associated Protein 2c at atomic resolution

LUC23081, projekt VaV

Název: Studium vnitřní dynamiky biologicky významných neuspořádaných proteinů

Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Studium vnitřní dynamiky biologicky významných neuspořádaných proteinů, INTER-COST

Citovat

KADEŘÁVEK, Pavel, Karel KUBÍČEK a Lukáš ŽÍDEK. Chapter 16 - Interactions among the three protein states. In Timir Tripathi and Vladimir N. Uversky. The Three Functional States of Proteins. Structured, Intrinsically Disordered, and Phase Separated. 525 B ST, STE 1900, SAN DIEGO, CA 92101-: Academic Press, 2024, s. 297-313. The Three Functional States of Proteins Structured, Intrinsically Disordered, and Phase Separated. ISBN 978-0-443-21809-5. Dostupné z: https://dx.doi.org/10.1016/C2023-0-00063-2.

@inbook{2481540,
   author = {Kadeřávek, Pavel and Kubíček, Karel and Žídek, Lukáš},
   address = {525 B ST, STE 1900, SAN DIEGO, CA 92101-},
   booktitle = {The Three Functional States of Proteins. Structured, Intrinsically Disordered, and Phase Separated},
   doi = {http://dx.doi.org/10.1016/C2023-0-00063-2},
   editor = {Timir Tripathi and Vladimir N. Uversky},
   keywords = {structured proteins; intrinsically disordered proteins; phase separated proteins; cellular life; health; disease},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {525 B ST, STE 1900, SAN DIEGO, CA 92101-},
   isbn = {978-0-443-21809-5},
   pages = {297-313},
   publisher = {Academic Press},
   title = {Chapter 16 - Interactions among the three protein states},
   url = {https://www.sciencedirect.com/book/9780443218095/the-three-functional-states-of-proteins},
   year = {2024}
}

TY  - CHAP
ID  - 2481540
AU  - Kadeřávek, Pavel - Kubíček, Karel - Žídek, Lukáš
PY  - 2024
TI  - Chapter 16 - Interactions among the three protein states
VL  - The Three Functional States of Proteins Structured, Intrinsically Disordered, and Phase Separated
PB  - Academic Press
CY  - 525 B ST, STE 1900, SAN DIEGO, CA 92101-
SN  - 9780443218095
KW  - structured proteins
KW  - intrinsically disordered proteins
KW  - phase separated proteins
KW  - cellular life
KW  - health
KW  - disease
UR  - https://www.sciencedirect.com/book/9780443218095/the-three-functional-states-of-proteins
N2  - Interactions between the three states of proteins (structured, intrinsically disordered, and phase separated) can be probed by a variety of experimental methods. First, we review fundamental physical forces determining structural features and intermolecular interactions of all three states of proteins. We classify individual contributions of the interactions, comment on their theoretical treatment, stress the importance of water as a solvent, and discuss the hierarchy of protein structures. Then we briefly mention methods of structure determination at the atomic resolution and describe in more detail selected methods probing specific features of intra- and intermolecular protein interactions. The selection includes various methods of nuclear magnetic resonance spectroscopy (including analysis of chemical shifts, relaxation effects, and measurements of translational diffusion and proton exchange) and methods reflecting hydrodynamic behavior, namely, analytical ultracentrifugation and small-angle X-ray scattering. The text does not have an ambition to provide actual protocols or a complete list of applications but tries to comment on the use of the methods for the three states of proteins.
ER  -

KADEŘÁVEK, Pavel, Karel KUBÍČEK a Lukáš ŽÍDEK. Chapter 16 - Interactions among the three protein states. In Timir Tripathi and Vladimir N. Uversky. \textit{The Three Functional States of Proteins. Structured, Intrinsically Disordered, and Phase Separated}. 525 B ST, STE 1900, SAN DIEGO, CA 92101-: Academic Press, 2024, s.~297-313. The Three Functional States of Proteins Structured, Intrinsically Disordered, and Phase Separated. ISBN~978-0-443-21809-5. Dostupné z: https://dx.doi.org/10.1016/C2023-0-00063-2.

Podrobný výpis o publikaci