Detection of obstetric anal sphincter injuries using machine
learning-assisted impedance spectroscopy: a prospective,
comparative, multicentre clinical study

J 2025

Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study

BORYCKA, Katarzyna; Marcel MLYNCZAK; Maciej ROSOL; Kacper KORZENIEWSKI; Piotr IWANOWSKI et. al.

Základní údaje

Originální název

Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study

Autoři

BORYCKA, Katarzyna; Marcel MLYNCZAK; Maciej ROSOL; Kacper KORZENIEWSKI; Piotr IWANOWSKI; Hynek HERMAN; Petr JANKŮ (203 Česká republika, domácí); Malgorzata UCHMAN-MUSIELAK; Erik DOSEDLA; Enrique Gonzalez DIAZ; Iwona SUDOL-SZOPINSKA; Michal MIK; Carlo RATTO a Antonino SPINELLI

Vydání

Scientific Reports, Berlin, NATURE RESEARCH, 2025, 2045-2322

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30214 Obstetrics and gynaecology

Stát vydavatele

Německo

Utajení

není předmětem státního či obchodního tajemství

Odkazy

URL

Impakt faktor

Impact factor: 3.900 v roce 2024

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1038/s41598-025-92392-z

UT WoS

001436277100005

EID Scopus

2-s2.0-86000102572

Klíčová slova anglicky

Obstetric anal sphincter injury (OASI); Anal sphincter; Perineal tear; Faecal incontinence; Rapid diagnostics; Clinical study; Impedance spectroscopy; Machine learning

Štítky

14110240, 14110611, rivok

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 2. 4. 2025 13:35, Mgr. Tereza Miškechová

Anotace

V originále

To evaluate the clinical performance and safety of the ONIRY system for obstetric anal sphincter injuries (OASI) detection versus three-dimensional endoanal ultrasound (EAUS). A prospective, comparative, multicentre, international study. Poland, Czechia, Slovakia, and Spain. 152 women between the first moments up to 8 weeks after vaginal delivery. Participants underwent EAUS and were allocated to groups based on OASIS classification: A (no perineal tear), B (1st or 2nd degree tear), or C (3rd or 4th degree, anal sphincters affected). Electric impedance was measured in the anal canal using the ONIRY system. The primary endpoint was the diagnostic outcome of impedance spectroscopy versus EAUS. Adverse events were collected. Part II involved in silico modelling and 10-time 10-fold cross-validation for automated analysis. Accuracy, sensitivity, and specificity. 30 women were allocated to group A, 61 to group B, and 61 to group C. The diagnostic outcome was determined for 147 participants. The accuracy, sensitivity, and specificity of the ML-assisted impedance spectroscopy were 87.0 +/- 0.5%, 90.6 +/- 2.0%, and 84.6 +/- 1.9%, respectively, compared with EAUS. After data cleaning, the performance metrics of the proposed final ML model for ONIRY were: 90.0 +/- 0.4%, 90.0 +/- 1.2%, and 90.0 +/- 0.7%, respectively. No adverse device effects or deficiencies were observed. By enabling early identification of sphincter injuries, ML-assisted impedance spectroscopy facilitates timely diagnosis and intervention, potentially reducing long-term complications such as faecal incontinence. Its rapid, bedside application in obstetric settings supports immediate postpartum care, complementing digital rectal examination and optimizing clinical decision-making.

Citovat

BORYCKA, Katarzyna; Marcel MLYNCZAK; Maciej ROSOL; Kacper KORZENIEWSKI; Piotr IWANOWSKI; Hynek HERMAN; Petr JANKŮ; Malgorzata UCHMAN-MUSIELAK; Erik DOSEDLA; Enrique Gonzalez DIAZ; Iwona SUDOL-SZOPINSKA; Michal MIK; Carlo RATTO a Antonino SPINELLI. Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study. Scientific Reports. Berlin: NATURE RESEARCH, 2025, roč. 15, č. 1, s. 1-13. ISSN 2045-2322. Dostupné z: https://doi.org/10.1038/s41598-025-92392-z.

@article{2488558,
   author = {Borycka, Katarzyna and Mlynczak, Marcel and Rosol, Maciej and Korzeniewski, Kacper and Iwanowski, Piotr and Herman, Hynek and Janků, Petr and UchmanandMusielak, Malgorzata and Dosedla, Erik and Diaz, Enrique Gonzalez and SudolandSzopinska, Iwona and Mik, Michal and Ratto, Carlo and Spinelli, Antonino},
   article_location = {Berlin},
   article_number = {1},
   doi = {https://doi.org/10.1038/s41598-025-92392-z},
   keywords = {Obstetric anal sphincter injury (OASI); Anal sphincter; Perineal tear; Faecal incontinence; Rapid diagnostics; Clinical study; Impedance spectroscopy; Machine learning},
   language = {eng},
   issn = {2045-2322},
   journal = {Scientific Reports},
   title = {Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study},
   url = {https://www.nature.com/articles/s41598-025-92392-z},
   volume = {15},
   year = {2025}
}

TY  - JOUR
ID  - 2488558
AU  - Borycka, Katarzyna - Mlynczak, Marcel - Rosol, Maciej - Korzeniewski, Kacper - Iwanowski, Piotr - Herman, Hynek - Janků, Petr - Uchman-Musielak, Malgorzata - Dosedla, Erik - Diaz, Enrique Gonzalez - Sudol-Szopinska, Iwona - Mik, Michal - Ratto, Carlo - Spinelli, Antonino
PY  - 2025
TI  - Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study
JF  - Scientific Reports
VL  - 15
IS  - 1
SP  - 1-13
EP  - 1-13
PB  - NATURE RESEARCH
SN  - 20452322
KW  - Obstetric anal sphincter injury (OASI)
KW  - Anal sphincter
KW  - Perineal tear
KW  - Faecal incontinence
KW  - Rapid diagnostics
KW  - Clinical study
KW  - Impedance spectroscopy
KW  - Machine learning
UR  - https://www.nature.com/articles/s41598-025-92392-z
N2  - To evaluate the clinical performance and safety of the ONIRY system for obstetric anal sphincter injuries (OASI) detection versus three-dimensional endoanal ultrasound (EAUS). A prospective, comparative, multicentre, international study. Poland, Czechia, Slovakia, and Spain. 152 women between the first moments up to 8 weeks after vaginal delivery. Participants underwent EAUS and were allocated to groups based on OASIS classification: A (no perineal tear), B (1st or 2nd degree tear), or C (3rd or 4th degree, anal sphincters affected). Electric impedance was measured in the anal canal using the ONIRY system. The primary endpoint was the diagnostic outcome of impedance spectroscopy versus EAUS. Adverse events were collected. Part II involved in silico modelling and 10-time 10-fold cross-validation for automated analysis. Accuracy, sensitivity, and specificity. 30 women were allocated to group A, 61 to group B, and 61 to group C. The diagnostic outcome was determined for 147 participants. The accuracy, sensitivity, and specificity of the ML-assisted impedance spectroscopy were 87.0 +/- 0.5%, 90.6 +/- 2.0%, and 84.6 +/- 1.9%, respectively, compared with EAUS. After data cleaning, the performance metrics of the proposed final ML model for ONIRY were: 90.0 +/- 0.4%, 90.0 +/- 1.2%, and 90.0 +/- 0.7%, respectively. No adverse device effects or deficiencies were observed. By enabling early identification of sphincter injuries, ML-assisted impedance spectroscopy facilitates timely diagnosis and intervention, potentially reducing long-term complications such as faecal incontinence. Its rapid, bedside application in obstetric settings supports immediate postpartum care, complementing digital rectal examination and optimizing clinical decision-making.
ER  -

BORYCKA, Katarzyna; Marcel MLYNCZAK; Maciej ROSOL; Kacper KORZENIEWSKI; Piotr IWANOWSKI; Hynek HERMAN; Petr JANKŮ; Malgorzata UCHMAN-MUSIELAK; Erik DOSEDLA; Enrique Gonzalez DIAZ; Iwona SUDOL-SZOPINSKA; Michal MIK; Carlo RATTO a Antonino SPINELLI. Detection of obstetric anal sphincter injuries using machine learning-assisted impedance spectroscopy: a prospective, comparative, multicentre clinical study. \textit{Scientific Reports}. Berlin: NATURE RESEARCH, 2025, roč.~15, č.~1, s.~1-13. ISSN~2045-2322. Dostupné z: https://doi.org/10.1038/s41598-025-92392-z.

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