BUČKOVÁ, Dana (203 Česká republika, garant), Lydie IZAKOVIČOVÁ HOLLÁ (203 Česká republika), Petr BENEŠ (203 Česká republika), Vladimír ZNOJIL (203 Česká republika) a Jiří VÁCHA (203 Česká republika)
Vydání
Allergy, Denmark, Munksgaard International Publishers, 2001, 0105-4538
Transforming growth factor beta (TGF-beta) is a pleiotropic cytokine with significant anti-inflammatory and immunosuppressive properties. The single base pair polymorphism located at -509 (C/T) in the promoter region of the TGF-beta1 gene was previously shown to be associated with elevated total serum IgE levels. We tested the hypothesis that polymorphic alleles of the TGF-beta1 gene are associated with allergies and asthma.