J 2001

Relationship of age and the body mass index to selected hypertensive complications in pregnancy

HRAZDILOVÁ, Olga, Vít UNZEITIG, Vladimír ZNOJIL, Lydie IZAKOVIČOVÁ-HOLLÁ, Petr JANKŮ et. al.

Basic information

Original name

Relationship of age and the body mass index to selected hypertensive complications in pregnancy

Authors

HRAZDILOVÁ, Olga (203 Czech Republic, guarantor), Vít UNZEITIG (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic), Lydie IZAKOVIČOVÁ-HOLLÁ (203 Czech Republic), Petr JANKŮ (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic)

Edition

International Journal of Gynecology and Obstetrics, Amsterodam, Elsevier, 2001, 0020-7292

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

Netherlands

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.635

RIV identification code

RIV/00216224:14110/01:00004363

Organization unit

Faculty of Medicine

UT WoS

000172548300006

Keywords in English

BMI; preeclampsia; age; hypertension; proteinuria; pregnancy
Změněno: 17/6/2009 12:50, prof. MUDr. Lydie Izakovičová Hollá, Ph.D.

Abstract

V originále

An older maternal age is considered to be a risk factor for a number of pregnancy-associated pathologies. Average weight increases with age. The aim of this study was to assess the effects of maternal age on selected pregnancy pathologies separately from the influence of maternal weight. The retrospective study included 910 women. The following parameters were evaluated: age, p-BMI (body mass index before pregnancy), hypertension, severe hypertension, preeclampsia, proteinuria, severe proteinuria, thrombembolic diseases, pregnancy duration and fetal hypotrophy. The correlation between the p-BMI and age was confirmed (P=0.001). After filtering away the mutual influence of age and p-BMI applying logistic regression, we proved a statistically high significant effect of p-BMI on the incidence of hypertension, severe hypertension, proteinuria, preeclamsia (P=0.001). The maternal age (cleared of the p-BMI) effects on severe hypertension (P=0.05). Age alone proved to be a risk factor for severe hypertension of the pregnant subjects. Increased risk for proteinuria, hypertension and preeclampsia is directly associated with p-BMI of the pregnant women, and thus only indirectly with their age.

Links

VS96097, research and development project
Name: Molekulární patofyziologie vybraných "civilizačních", multigenně podmíněných chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of selected multigenic related to civilization diseases