MOHAMED, Walid Fathalla and Pavel PAZDERA. The regioselectivity of the thioamide moiety against electrophiles and nucleophiles. In Sborník príspevkov 53. zjazd Chemických spoločností. 1st ed. Banká Bystrica: FPV Univerzita Mateja Bela v Banskej Bystrici, 2001, p. 229-230. 1. ISBN 80-89029-22-1.
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Basic information
Original name The regioselectivity of the thioamide moiety against electrophiles and nucleophiles
Authors MOHAMED, Walid Fathalla and Pavel PAZDERA.
Edition 1. vyd. Banká Bystrica, Sborník príspevkov 53. zjazd Chemických spoločností, p. 229-230, 1. 2001.
Publisher FPV Univerzita Mateja Bela v Banskej Bystrici
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10401 Organic chemistry
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/01:00005236
Organization unit Faculty of Science
ISBN 80-89029-22-1
Keywords in English Thioamides; thioureas; regioselectivity
Tags regioselectivity, Thioamides, thioureas
Changed by Changed by: doc. RNDr. Pavel Pazdera, CSc., učo 2276. Changed: 8/1/2002 16:30.
Abstract
Several research workers investigated the S / N nucleophilic character competition of the thioamide moieties (included in cyclic and acyclic systems) by the intermolecular reaction with electrophiles. The discrimination between the S-alkylation and the N-alkylation were briefly published for several cases but the reason for N- and S-atoms contributions were not yet described. Our communication will simply explain the N- and S-atoms involvement in reactions on the model compound 4-methyl-1-thioxo-1,2,4,5-tetrahydro[1,2,4]triazolo[4,3-a]quinazolin-5-one.
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MSM 143100011, plan (intention)Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů
Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles
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