ZITTERBART, Karel and Renata VESELSKÁ. Effect of retinoic acid on the actin cytoskeleton in HL-60 cells. Neoplasma. Bratislava: Slovak Academic Press, 2001, vol. 48, No 6, p. 456-461. ISSN 0028-2685.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Effect of retinoic acid on the actin cytoskeleton in HL-60 cells
Authors ZITTERBART, Karel (203 Czech Republic, guarantor) and Renata VESELSKÁ (203 Czech Republic).
Edition Neoplasma, Bratislava, Slovak Academic Press, 2001, 0028-2685.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10600 1.6 Biological sciences
Country of publisher Slovakia
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.637
RIV identification code RIV/00216224:14110/01:00005470
Organization unit Faculty of Medicine
UT WoS 000173672300006
Keywords in English Apoptosis; cytoskeleton; F-actin; all-trans retinoic acid; differentiation; HL-60 cells
Tags all-trans retinoic acid, apoptosis, Cytoskeleton, differentiation, F-actin, HL-60 cells
Tags International impact, Reviewed
Changed by Changed by: MUDr. Karel Zitterbart, Ph.D., učo 21262. Changed: 11/4/2010 23:37.
Abstract
The morphological changes in actin cytoskeleton, taking place during apoptosis in cells of the human leukemic HL-60 cell line, were described. It is concluded that the actin cytoskeleton is a dynamic structure actively involved in the executive phase of the process of apoptosis. It is suggested that the rearrangement of the microfilament network and its subsequent degradation are necessary for the main morphological changes of apoptotic cells, i.e., plasma membrane blebbing and apoptotic bodies formation.
Links
GA304/00/0403, research and development projectName: Změny cytoskeletu buněk nádorových linií v průběhu indukované apoptózy v závislosti na stádiu diferenciace.
Investor: Czech Science Foundation, Changes of the cytoskeleton in tumour cell lines during induced apoptosis in relation to different stages of differentiation
PrintDisplayed: 26/4/2024 13:48