| JURAJDA, Michal, Jan MUŽÍK, Lydie IZAKOVIČOVÁ HOLLÁ a Jiří VÁCHA. A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene. Molecular and Cellular Probes. London: Academic Press Ltd, London, 2002, roč. 16, č. 1, s. 63-66. ISSN 0890-8508. |
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@article{403332,
author = {Jurajda, Michal and Mužík, Jan and Izakovičová Hollá, Lydie and Vácha, Jiří},
article_location = {London},
article_number = {1},
keywords = {single nucleotide polymorphism; matrix metalloproteinase},
language = {eng},
issn = {0890-8508},
journal = {Molecular and Cellular Probes},
title = {A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene},
volume = {16},
year = {2002}
}
TY - JOUR
ID - 403332
AU - Jurajda, Michal - Mužík, Jan - Izakovičová Hollá, Lydie - Vácha, Jiří
PY - 2002
TI - A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene
JF - Molecular and Cellular Probes
VL - 16
IS - 1
SP - 63
EP - 63
PB - Academic Press Ltd, London
SN - 08908508
KW - single nucleotide polymorphism
KW - matrix metalloproteinase
N2 - Matrix metalloproteinase-1 (MMP-1) is a member of the matrix metalloproteinase enzyme family that degrades components of the extracellular matrix. Recent studies have demonstrated several polymorphic sites in the promoter of the MMP-1 gene. A newly identified single nucleotide polymorphism (SNP) at position -519 in the promoter region of the MMP-1 gene is reported. This polymorphism consists in a guanine to adenine substitution. A linkage between polymorphisms -519A/G and -1607 1G/2G was also studied.
ER -
JURAJDA, Michal, Jan MUŽÍK, Lydie IZAKOVIČOVÁ HOLLÁ a Jiří VÁCHA. A newly identified single nucleotide polymorphism in the promoter of the matrix metalloproteinase-1 gene. \textit{Molecular and Cellular Probes}. London: Academic Press Ltd, London, 2002, roč.~16, č.~1, s.~63-66. ISSN~0890-8508.
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