GOLDBERGOVÁ, Monika, Lenka ŠPINAROVÁ, Jindřich ŠPINAR, Svatava TSCHÖPLOVÁ and Anna VAŠKŮ. Polymorphisms in inflammatory genes (TNFalpha, TNFbeta and TNFalpha-converting enzyme) in chronic heart failure. 2002.
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Basic information
Original name Polymorphisms in inflammatory genes (TNFalpha, TNFbeta and TNFalpha-converting enzyme) in chronic heart failure
Authors GOLDBERGOVÁ, Monika (203 Czech Republic, guarantor), Lenka ŠPINAROVÁ (203 Czech Republic), Jindřich ŠPINAR (203 Czech Republic), Svatava TSCHÖPLOVÁ (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic).
Edition 2002.
Other information
Original language English
Type of outcome Conference abstract
Field of Study Genetics and molecular biology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/02:00006182
Organization unit Faculty of Medicine
Keywords in English chronic heart failure; gene; polymorphism; TNF
Tags chronic heart failure, gene, polymorphism, TNF
Changed by Changed by: prof. RNDr. Monika Pávková Goldbergová, Ph.D., učo 9447. Changed: 6/4/2010 12:31.
Abstract
Pro-inflammatory peptides as TNFalpha, TNFbeta, as well as TNFalpha-converting enzyme (TACE) can be involved in the onset and/or progression of cardiovascular diseases. The aim of the study was to prove associations of three frequent polymorphisms in the genes (G(-308)A TNFalpha, NcoI TNFbeta and 2A/3A TACE) with chronic heart failure.
Links
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
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