Detailed Information on Publication Record
2002
Synthesis of New 4-(4-(4-Methoxyphenyl)-5-(2-phenylquinazolin-4-yl)-1,3-Thiazol-2-yl)morpholine and N4-(5-(4-Methoxyphenyl)-1,3-oxathiol-2-yliden)-(2-phenylquinazolin-4-yl)-amine
MOHAMED, Walid Fathalla, Jaromír MAREK and Pavel PAZDERABasic information
Original name
Synthesis of New 4-(4-(4-Methoxyphenyl)-5-(2-phenylquinazolin-4-yl)-1,3-Thiazol-2-yl)morpholine and N4-(5-(4-Methoxyphenyl)-1,3-oxathiol-2-yliden)-(2-phenylquinazolin-4-yl)-amine
Authors
MOHAMED, Walid Fathalla (818 Egypt), Jaromír MAREK (203 Czech Republic) and Pavel PAZDERA (203 Czech Republic, guarantor)
Edition
Heterocyclic Communications, London, Freund Publishing House, 2002, 0793-0283
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10401 Organic chemistry
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.326
RIV identification code
RIV/00216224:14310/02:00006268
Organization unit
Faculty of Science
Keywords in English
quinazolines; 1;3-oxathioles; 1;3-thiazoles; domino-reaction; cyclization; retro-cyclization
Změněno: 1/11/2006 07:27, doc. RNDr. Pavel Pazdera, CSc.
Abstract
V originále
The reaction of N3,N3-(3-oxapentan-1,5-diyl)-N1-(2-phenyl-3,4-dihydroquinazolin-4-yliden)thiourea with 4-methoxyphenacyl bromide afforded either the kinetically controlled reversible reaction product N4-[5-(4-methoxyphenyl)-1,3-oxathiol-2-yliden]-(2-phenylquinazolin-4-yl)-amine or the thermo-dynamically controlled reaction product 4-[4-(4-methoxyphenyl)-5-(2-phenylquinazolin-4-yl) -4,5-dihydro-1,3-thiazol-2-yl]morpholine via domino-reaction by two different reaction pathways.
Links
| GA203/01/1333, research and development project |
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| MSM 143100011, plan (intention) |
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