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@article{404956, author = {Nováková, Marie and Nováková, Zuzana and Moudr, Jiří}, article_location = {Brno}, article_number = {4}, keywords = {Mechanical restitution; papillary muscle; heart; left and right ventricles; guinea pig}, language = {eng}, issn = {1211-3395}, journal = {Scripta medica}, title = {Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations}, volume = {75}, year = {2002} }
TY - JOUR ID - 404956 AU - Nováková, Marie - Nováková, Zuzana - Moudr, Jiří PY - 2002 TI - Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations JF - Scripta medica VL - 75 IS - 4 SP - 187 EP - 187 PB - Lékařská fakulta Brno SN - 12113395 KW - Mechanical restitution KW - papillary muscle KW - heart KW - left and right ventricles KW - guinea pig N2 - The study was focused on identification of possible differences in the onset and time course of mechanical restitution in guinea pig multicellular heart preparations, i.e., papillary muscles from the right and left ventricles. Stimulated twitches of both preparations mounted in a horizontal perfusion bath were recorded simultaneously. Mechanical restitution curves were constructed at 25C and 35C and at stimulation rates of 0.5 Hz, 1 Hz and 2 Hz. No statistically significant differences in restitution curves of both preparations were found. It can be concluded that, in the assessment of mechanical behaviour of the heart, the guinea pig left ventricular papillary muscle appears to be a suitable substitute for the conventionally employed right ventricular papillary muscles. ER -
NOVÁKOVÁ, Marie, Zuzana NOVÁKOVÁ and Jiří MOUDR. Mechanical Restitution in Left and Right Guinea Pig Ventricular Preparations. \textit{Scripta medica}. Brno: Lékařská fakulta Brno, 2002, vol.~75, No~4, p.~187-194. ISSN~1211-3395.
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