| ŽOURKOVÁ, Alexandra a Eva HADAŠOVÁ. Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment. Journal of Sex and Marital Therapy. Philadelphia,USA: Taylor and Francis Health Sciences, 2002, roč. 28, č. 5, s. 451-461. ISSN 0092-623X. |
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@article{405467,
author = {Žourková, Alexandra and Hadašová, Eva},
article_location = {Philadelphia,USA},
article_number = {5},
keywords = {sexual dysfunction; CYP2D6; paroxetine; poor metabolizer},
language = {eng},
issn = {0092-623X},
journal = {Journal of Sex and Marital Therapy},
title = {Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment},
volume = {28},
year = {2002}
}
TY - JOUR
ID - 405467
AU - Žourková, Alexandra - Hadašová, Eva
PY - 2002
TI - Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment
JF - Journal of Sex and Marital Therapy
VL - 28
IS - 5
SP - 451
EP - 451
PB - Taylor and Francis Health Sciences
SN - 0092623X
KW - sexual dysfunction
KW - CYP2D6
KW - paroxetine
KW - poor metabolizer
N2 - This article describes the incidence of sexual dysfunction in 30 patients subjected to long-term treatment by paroxetine in dependence on the P 450 CYP 2D6 isoenzyme metabolic status. Measured on the Arizona Sexual Experience Scale (ASEX; McGahuey, Delgado, & Gelenberg, 1999), the incidence of sexual dysfunction inpatients converted to CYP 2D6 poor metabolizers was markedly higher compared with patients who had no history of such conversion, a difference that reached the level of statistical significance. Our article discusses the incidence of sexual dysfunction in connection with reduced CYP 2D6 capacity.
ER -
ŽOURKOVÁ, Alexandra a Eva HADAŠOVÁ. Relationship Between CYP 2D6 Metabolic Status and Sexual Dysfunction in Paroxetine Treatment. \textit{Journal of Sex and Marital Therapy}. Philadelphia,USA: Taylor and Francis Health Sciences, 2002, roč.~28, č.~5, s.~451-461. ISSN~0092-623X.
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