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@inproceedings{407175,
author = {Nováková, Marie and Provazník, Ivo},
address = {Vienna},
booktitle = {Proceedings of International Federation of Medical and Biological Engineering},
edition = {3},
keywords = {cardiac contractility; side effects of neuroleptics; sigma receptor; wavelet analysis},
language = {eng},
location = {Vienna},
isbn = {3-901351-62-0},
pages = {554-556},
publisher = {EMBEC 02},
title = {Time- and Time-Frequency Analysis of Contractility and Desensitisation in Multicellular Heart Preparations},
year = {2002}
}
TY - JOUR
ID - 407175
AU - Nováková, Marie - Provazník, Ivo
PY - 2002
TI - Time- and Time-Frequency Analysis of Contractility and Desensitisation in Multicellular Heart Preparations
VL - I.
PB - EMBEC 02
CY - Vienna
SN - 3901351620
KW - cardiac contractility
KW - side effects of neuroleptics
KW - sigma receptor
KW - wavelet analysis
N2 - The aim of this study was to examine the effect of sigma receptor ligand haloperidol in guinea pig atrial preparations. Stimulated contractions were recorded and analysed by time- and time-frequency methods. The analysis revealed that the compound exerts marked positive inotropic effect. This was significantly less pronounced in case of repeated drug administration. We conclude that sigma receptors in guinea pig atria undergo a desensitization process.
ER -
NOVÁKOVÁ, Marie and Ivo PROVAZNÍK. Time- and Time-Frequency Analysis of Contractility and Desensitisation in Multicellular Heart Preparations (Time- and Time-frequency analysis of Contractility and Desensitisation in Multicellular Heart Preparations). In \textit{Proceedings of International Federation of Medical and Biological Engineering}. 3rd ed. Vienna: EMBEC 02, 2002, p.~554-556. I. ISBN~3-901351-62-0.
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