Effects of endocannabinoids on agonistic behaviour in mice

NOVÁKOVÁ, Jana, Jana VINKLEROVÁ a Alexandra ŠULCOVÁ. Effects of endocannabinoids on agonistic behaviour in mice. In Abstracts of Workshop: Psychopharmacology of Cannabis and Ecstasy. Brno: LF MU Brno, 2002, s. 51.

Základní údaje

Originální název

Effects of endocannabinoids on agonistic behaviour in mice

Autoři

NOVÁKOVÁ, Jana (203 Česká republika, garant), Jana VINKLEROVÁ (203 Česká republika) a Alexandra ŠULCOVÁ (203 Česká republika)

Vydání

Brno, Abstracts of Workshop: Psychopharmacology of Cannabis and Ecstasy, s. 51-51, 2002

Nakladatel

LF MU Brno

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Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30104 Pharmacology and pharmacy

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/02:00006944

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

CB1 and CB2 cannabinoid receptor subtypes; endocannabinoids; agonistic behaviour; mice

Štítky

agonistic behaviour, endocannabinoids, mice

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Anotace

V originále

The present study was designed to ascertain behavioural effects of novel endocannabinoid ligand noladin ether using the model of agonistic behaviour in mice. In aggressive singly-housed mice, noladin did not show marked changes in behavioural activities. The only significant effect recorded was the significant inhibition of sociable sniffing. In timid isolates, noladin elicited a significant aggresssogenic action with the impairment of the locomotor activity. Thus, the behavioural noladin profile found did not fully resemble that of anandamide which in our earlier experiments exerted a significant antiaggressive effects using the model of mouse agonistic social interactions.