NOVÁKOVÁ, Jana, Jana VINKLEROVÁ and Alexandra ŠULCOVÁ. Effects of endocannabinoids on agonistic behaviour in mice. In Abstracts of Workshop: Psychopharmacology of Cannabis and Ecstasy. Brno: LF MU Brno, 2002, p. 51.
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Basic information
Original name Effects of endocannabinoids on agonistic behaviour in mice
Authors NOVÁKOVÁ, Jana (203 Czech Republic, guarantor), Jana VINKLEROVÁ (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic).
Edition Brno, Abstracts of Workshop: Psychopharmacology of Cannabis and Ecstasy, p. 51-51, 2002.
Publisher LF MU Brno
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/02:00006944
Organization unit Faculty of Medicine
Keywords in English CB1 and CB2 cannabinoid receptor subtypes; endocannabinoids; agonistic behaviour; mice
Tags agonistic behaviour, endocannabinoids, mice
Changed by Changed by: MUDr. Jana Nováková, Ph.D., učo 2376. Changed: 27/5/2003 19:53.
Abstract
The present study was designed to ascertain behavioural effects of novel endocannabinoid ligand noladin ether using the model of agonistic behaviour in mice. In aggressive singly-housed mice, noladin did not show marked changes in behavioural activities. The only significant effect recorded was the significant inhibition of sociable sniffing. In timid isolates, noladin elicited a significant aggresssogenic action with the impairment of the locomotor activity. Thus, the behavioural noladin profile found did not fully resemble that of anandamide which in our earlier experiments exerted a significant antiaggressive effects using the model of mouse agonistic social interactions.
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