PAVELKA, Stanislav. A survey of effects of excessive bromide intake on iodine metabolism in the rat. In Macro and Trace Elements/Mengen- und Spurenelemente (Anke M., Müller R., Schäfer U., Stoeppler M., eds.) [IF=n.a.]. Leipzig: SCHUBERT-Verlag, 2002, p. 567-574. Agricult., Biological, Environmental, Nutrit., 21. ISBN 3-929526-73-5.
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Basic information
Original name A survey of effects of excessive bromide intake on iodine metabolism in the rat
Name in Czech Přehled účinků nadbytečného příjmu bromidu na metabolismus jodu u potkana
Authors PAVELKA, Stanislav (203 Czech Republic, guarantor).
Edition Leipzig, Macro and Trace Elements/Mengen- und Spurenelemente (Anke M., Müller R., Schäfer U., Stoeppler M., eds.) [IF=n.a.], p. 567-574, 8 pp. Agricult., Biological, Environmental, Nutrit., 21, 2002.
Publisher SCHUBERT-Verlag
Other information
Original language English
Type of outcome Chapter(s) of a specialized book
Field of Study 30202 Endocrinology and metabolism
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/02:00007113
Organization unit Faculty of Science
ISBN 3-929526-73-5
Keywords in English bromide; iodine; metabolism; rat; thyroid
Tags bromide, iodine, metabolism, rat, thyroid
Tags International impact, Reviewed
Changed by Changed by: doc. RNDr. Stanislav Pavelka, CSc., učo 313. Changed: 10/4/2010 14:36.
Abstract
We studied the effects of an increased bromide intake, at different levels of iodine supply to the organism, on various aspects of iodine metabolism in the rat. A reduction of the food intake and consequently of the body weight gain was observed in rats drinking water with the highest bromide concentration (5 g bromide per liter). An increase in the relative weight of the thyroids and a significant decrease in the 24-h uptake of radioiodide by the thyroids were also found in these animals, especially in those fed a research low-iodine diet. The concentration ratio [I]/[Br] in the thyroids proved to be a very sensitive marker of even negligibly increased bromide intake in the rats.
Links
NJ6109, research and development projectName: Interference bromidu z životního prostředí s metabolismem jodu ve štítné žláze a dalších tkáních
Investor: Ministry of Health of the CR, Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues
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