Effects of high bromide intake on various aspects of iodine metabolism in the rat

PAVELKA, Stanislav, Arnošt BABICKÝ and Miloslav VOBECKÝ. Effects of high bromide intake on various aspects of iodine metabolism in the rat. In Proceedings, 6th Workshop of Biochemists and Molecular Biologists. Brno: Masaryk University, 2002, p. 60-61. ISBN 80-210-2777-0.

Basic information

• Original name: Effects of high bromide intake on various aspects of iodine metabolism in the rat
• Authors: PAVELKA, Stanislav (203 Czech Republic, guarantor), Arnošt BABICKÝ (203 Czech Republic) and Miloslav VOBECKÝ (203 Czech Republic).
• Edition: Brno, Proceedings, 6th Workshop of Biochemists and Molecular Biologists, p. 60-61, 2 pp. 2002.
• Publisher: Masaryk University

Other information

• Original language: English
• Type of outcome: Proceedings paper
• Field of Study: 30105 Physiology
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/02:00007116
• Organization unit: Faculty of Science
• ISBN: 80-210-2777-0
• Keywords in English: bromide; iodine; metabolism; rat; thyroid
• Tags: bromide, iodine, metabolism, rat, thyroid

Abstract

We have demonstrated a significant influence of an excessively high bromide intake in adult male and female rats on the kinetics of radioiodide uptake and elimination by the thyroid gland, skin, and mammary glands. From the results of our experiments, we concluded that high bromide levels in the organism of experimental animals could affect their iodine metabolism in two parallel ways: by a decrease in iodide accumulation in the thyroid, and by a rise in iodide excretion from the body by the kidneys.

Links

• NJ6109, research and development project: Name: Interference bromidu z životního prostředí s metabolismem jodu ve štítné žláze a dalších tkáních

Investor: Ministry of Health of the CR, Interference of bromide from the environment with iodine metabolism in the thyroid gland and other tissues