2003
Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections
RŮŽIČKOVÁ, Vladislava, Roman PANTŮČEK, Petr PETRÁŠ, Jiří DOŠKAŘ, Ivo SEDLÁČEK et. al.Základní údaje
Originální název
Molecular typing of exfoliative toxin-producing Staphylococcus aureus strains involved in epidermolytic infections
Název česky
Molekulární typizace kmenů Staphylococcus aureus produkujících exfoliativní toxiny a podílejících se na epidermolytických infekcích
Autoři
RŮŽIČKOVÁ, Vladislava (203 Česká republika, garant), Roman PANTŮČEK (203 Česká republika), Petr PETRÁŠ (203 Česká republika), Jiří DOŠKAŘ (203 Česká republika), Ivo SEDLÁČEK (203 Česká republika) a Stanislav ROSYPAL (203 Česká republika)
Vydání
International Journal of Medical Microbiology, München, Germany, Urban & Fischer Verlag, 2003, 1438-4221
Další údaje
Jazyk
angličtina
Typ výsledku
Článek v odborném periodiku
Obor
Genetika a molekulární biologie
Stát vydavatele
Německo
Utajení
není předmětem státního či obchodního tajemství
Odkazy
Impakt faktor
Impact factor: 2.583
Kód RIV
RIV/00216224:14310/03:00009834
Organizační jednotka
Přírodovědecká fakulta
UT WoS
000181489500014
Klíčová slova anglicky
Bacterial Typing Techniques; DNA; Staphylococcus aureus; Exfoliative Toxin; Nucleic Acid Hybridization; Ribotyping; Pulsed Field-Gel Electrophoresis
Štítky
Příznaky
Mezinárodní význam, Recenzováno
Změněno: 1. 7. 2009 18:38, prof. RNDr. Roman Pantůček, Ph.D.
V originále
Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affected by an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted in the determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged impetigo infections.
Česky
Pulsed-field gel electrophoresis, ribotyping, PCR ribotyping as well as prophage carriage were used for the study of genetic relationship in a set of sixteen exfoliative toxin (ET) producing strains of Staphylococcus aureus isolated from infants affected by an epidermolytic disease in two maternity hospitals in the Czech Republic. These molecular techniques made it possible to distinguish unambiguously the genetically unrelated ET-positive strains. The comparison of various genomic profiles resulted in the determination of nine different genotypes. Three strains secreted combined ETA+ETB, and the others produced ETA and enterotoxin C or TSST-1. Evidence was given that the isolates causing the epidermolytic diseases disseminated in both the maternity hospitals did not originate from a single source or the common ancestor. Close proximity of neonates to a person colonised or infected by ET-positive staphylococci seems to be the most presumptive risk factor associated with the emerged impetigo infections.
Návaznosti
| MSM 143100008, záměr |
|