Quantitative modelling of effect of transverse-axial tubular
system on electricalactivity of cardiac cells: Development of
model

D 2002

Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model

PÁSEK, Michal, Georges. CHRISTÉ a Jiří ŠIMURDA

Základní údaje

Originální název

Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model

Autoři

PÁSEK, Michal (203 Česká republika, garant), Georges. CHRISTÉ (250 Francie) a Jiří ŠIMURDA (203 Česká republika)

Vydání

Svratka, Engineering Mechanics 2002, od s. 1-2, 2 s. 2002

Nakladatel

Národní konference s mezinárodní účastí

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30105 Physiology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/02:00007139

Organizační jednotka

Lékařská fakulta

ISBN

80-86246-18-3

Klíčová slova anglicky

cardiac cell; transverse-axial tubular system; quantitative modelling

Štítky

Cardiac cell, Quantitative modelling, transverse-axial tubular system

Změněno: 28. 5. 2003 18:57, doc. Ing. Michal Pásek, Ph.D.

Anotace

V originále

The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many recent experimental works, it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. In our previous work [27], the basic properties of TAT-system were formulated and preliminary simulations characterizing its effect on cellular electrical activity realised. In this article, we describe the design of a more complex model of ventricular myocyte based mostly on data from guinea pig. The model integrates the description of electrical activity of surface and tubular membranes with the detailed description of mechanisms controlling the intracellular and tubular ion concentrations.

Citovat

PÁSEK, Michal, Georges. CHRISTÉ a Jiří ŠIMURDA. Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model. In Engineering Mechanics 2002. Svratka: Národní konference s mezinárodní účastí, 2002, s. 1-2. ISBN 80-86246-18-3.

@inproceedings{483046,
   author = {Pásek, Michal and Christé, Georges. and Šimurda, Jiří},
   address = {Svratka},
   booktitle = {Engineering Mechanics 2002},
   keywords = {cardiac cell; transverse-axial tubular system; quantitative modelling},
   language = {eng},
   location = {Svratka},
   isbn = {80-86246-18-3},
   pages = {1-2},
   publisher = {Národní konference s mezinárodní účastí},
   title = {Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model},
   year = {2002}
}

TY  - JOUR
ID  - 483046
AU  - Pásek, Michal - Christé, Georges. - Šimurda, Jiří
PY  - 2002
TI  - Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model
PB  - Národní konference s mezinárodní účastí
CY  - Svratka
SN  - 8086246183
KW  - cardiac cell
KW  - transverse-axial tubular system
KW  - quantitative modelling
N2  - The transverse-axial tubular system (TAT-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many recent experimental works, it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. In our previous work [27], the basic properties of TAT-system were formulated and preliminary simulations characterizing its effect on cellular electrical activity realised. In this article, we describe the design of a more complex model of ventricular myocyte based mostly on data from guinea pig. The model integrates the description of electrical activity of surface and tubular membranes with the detailed description of mechanisms controlling the intracellular and tubular ion concentrations.
ER  -

PÁSEK, Michal, Georges. CHRISTÉ a Jiří ŠIMURDA. Quantitative modelling of effect of transverse-axial tubular system on electricalactivity of cardiac cells: Development of model. In \textit{Engineering Mechanics 2002}. Svratka: Národní konference s mezinárodní účastí, 2002, s.~1-2. ISBN~80-86246-18-3.

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