Quantitative modelling of effect of transverse-axial tubular
system on electrical activity of cardiac cells under low [K]e)

D 2002

Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e)

PÁSEK, Michal, Georges CHRISTÉ a Jiří ŠIMURDA

Základní údaje

Originální název

Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e)

Autoři

PÁSEK, Michal (203 Česká republika, garant), Georges CHRISTÉ (250 Francie) a Jiří ŠIMURDA (203 Česká republika)

Vydání

16.Brno. Brno University of Technology, Analysis of biomedical signals and images, od s. 424-426, 3 s. 2002

Nakladatel

Vutium Press

Další údaje

Jazyk

angličtina

Typ výsledku

Stať ve sborníku

Obor

30105 Physiology

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/02:00007142

Organizační jednotka

Lékařská fakulta

ISBN

80-214-2120-7

UT WoS

000178613000133

Klíčová slova anglicky

ventricular cell; low external [K]; tubular system; quantitative modelling

Štítky

low external [K], Quantitative modelling, tubular system, ventricular cell

Změněno: 25. 6. 2009 16:24, doc. Ing. Michal Pásek, Ph.D.

Anotace

V originále

In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K]e.

Citovat

PÁSEK, Michal, Georges CHRISTÉ a Jiří ŠIMURDA. Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e). In Analysis of biomedical signals and images. 16.Brno. Brno University of Technology: Vutium Press, 2002, s. 424-426. ISBN 80-214-2120-7.

@inproceedings{483054,
   author = {Pásek, Michal and Christé, Georges and Šimurda, Jiří},
   address = {Brno University of Technology},
   booktitle = {Analysis of biomedical signals and images},
   edition = {16.Brno},
   keywords = {ventricular cell; low external [K]; tubular system; quantitative modelling},
   language = {eng},
   location = {Brno University of Technology},
   isbn = {80-214-2120-7},
   pages = {424-426},
   publisher = {Vutium Press},
   title = {Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e)},
   year = {2002}
}

TY  - JOUR
ID  - 483054
AU  - Pásek, Michal - Christé, Georges - Šimurda, Jiří
PY  - 2002
TI  - Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e)
PB  - Vutium Press
CY  - Brno University of Technology
SN  - 8021421207
KW  - ventricular cell
KW  - low external [K]
KW  - tubular system
KW  - quantitative modelling
N2  - In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K]e.
ER  -

PÁSEK, Michal, Georges CHRISTÉ a Jiří ŠIMURDA. Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K]e). In \textit{Analysis of biomedical signals and images}. 16.Brno. Brno University of Technology: Vutium Press, 2002, s.~424-426. ISBN~80-214-2120-7.

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