Quantitative Analysis of Chiral Compounds from Unresolved Peaks in Capillary Electrophoresis using Multivariate Calibration with Experimental Design and Artificial Neural Networks

DOHNAL, Vlastimil; Hua LI; Marta FARKOVÁ and Josef HAVEL. Quantitative Analysis of Chiral Compounds from Unresolved Peaks in Capillary Electrophoresis using Multivariate Calibration with Experimental Design and Artificial Neural Networks. Chirality. New York: John Wiley & Sons, Inc., 2002, vol. 14, No 6, p. 509-518. ISSN 0899-0042.

Basic information

Original name

Quantitative Analysis of Chiral Compounds from Unresolved Peaks in Capillary Electrophoresis using Multivariate Calibration with Experimental Design and Artificial Neural Networks

Authors

DOHNAL, Vlastimil; Hua LI; Marta FARKOVÁ and Josef HAVEL

Edition

Chirality, New York, John Wiley & Sons, Inc. 2002, 0899-0042

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Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10406 Analytical chemistry

Country of publisher

United States of America

Confidentiality degree

is not subject to a state or trade secret

Impact factor

Impact factor: 1.575

Organization unit

Faculty of Science

UT WoS

000175962600011

Tags

International impact, Reviewed

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Abstract

In the original language

Quantitation of optical isomers can be achieved even from incompletely resolved peaks with a multivariate calibration applying a combination of experimental design and artificial neural networks (ANN). Using the proposed approach, method development can be more efficient and analysis time shortened while quantitation of optical isomers with acceptable precision (+-1-3%) can be achieved.