ZHI, Z., Viktor DRAŽAN, V.M. MIRSKY and O.S WOLFBEIS. Electrocatalytic activity of DNA. Electrochemistry in Microscopic and Molecular Dimensions. In 53-rd Annual Meeting of the International Society of Electrochemistry.Symposium 3: Bioelectrochemistry. Book of Abstracts. Dusseldorf, Germany: ISE, 2002, p. 105.
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Basic information
Original name Electrocatalytic activity of DNA. Electrochemistry in Microscopic and Molecular Dimensions
Authors ZHI, Z. (276 Germany), Viktor DRAŽAN (203 Czech Republic, guarantor), V.M. MIRSKY (643 Russian Federation) and O.S WOLFBEIS (276 Germany).
Edition Dusseldorf, Germany, 53-rd Annual Meeting of the International Society of Electrochemistry.Symposium 3: Bioelectrochemistry. Book of Abstracts, p. 105-105, 2002.
Publisher ISE
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10610 Biophysics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Keywords in English DNA; electrocatalytic activity of DNA;
Tags DNA, electrocatalytic activity of DNA
Changed by Changed by: prof. RNDr. Vladimír Vetterl, DrSc., učo 1954. Changed: 30/1/2003 17:59.
Abstract
It has been shown, that a formation of a self-assembled monolayer of single-stranded thiol-terminated nucleotides (HS-ssDNA) on gold electrodes leads to a multifold increase of electrochemical signals from anionic red/ox marker, dissolved in aqueous solution. The measurements were performed by cyclovoltametry and impedance spectroscopy. Experimental conditions where the DNA-coupled electrocatalysis is observed were evaluated. A binding of double-stranded thiol-terminated DNA to gold electrodes does not provide any eletrocatalytic effect. DNA hybridisation in solution led to increase of electrochemical activity.
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GA203/00/P081, research and development projectName: Adsorpce bází nukleových kyselin a jejich derivátů na elektrodách
GV204/97/K084, research and development projectName: Elektrody modifikované nukleovými kyselinami a bílkovinami. Nové nástroje v biochemickém a biomedicínském výzkumu
Investor: Czech Science Foundation, Electrodes modified with nucleic acids and proteins. New tools in biochemical and biomedical research
IAA4004002, research and development projectName: Struktura a interakce nukleových kyselin a polypeptidů na površích kovů
Investor: Academy of Sciences of the Czech Republic, Structure and Interaction of Nucleic Acids on Metal Surfaces
IBS5004107, research and development projectName: Aplikace biofyzikálních metod v biotechnologické a klinické praxi
Investor: Academy of Sciences of the Czech Republic, Application of biophysical methods in biotechnological and clinical praxis
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