HPLC on chiral nonracemic sorbents with circular dichroism
detection: Stereoisomers formed by 1,3-dipolar cycloadditions.

J 2003

HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions.

POSPÍŠIL, Jiří, Martin TRÁVNÍČEK, Albrecht MANNSCHRECK and Milan POTÁČEK

Basic information

Original name

HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions.

Authors

POSPÍŠIL, Jiří (203 Czech Republic), Martin TRÁVNÍČEK (203 Czech Republic), Albrecht MANNSCHRECK (276 Germany) and Milan POTÁČEK (203 Czech Republic, guarantor)

Edition

Chemické Listy, Praha, Česká společnost chemická, 2003, 0009-2770

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10401 Organic chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.345

RIV identification code

RIV/00216224:14310/03:00009500

Organization unit

Faculty of Science

Keywords in English

HPLC; chiral nonracemic sorbents; circular dichroism detection; stereoisomers; 1;3-dipolar cycloaddition

Abstract

V originále

The stereoisomers of several 1,3-dipolar cycloadducts were analysed without previous preparative separation, by HPLC on chiral nonracemic sorbents. This technique contributed significantly to the chemical purity checking, to the determination of the number of stereoisomers present, to the measurement of their relative proportions and to their characterization by retention factors and the circular dichroism (CD) properties. The detection with a CD instrument, in addition to a usual UV photometer, was carried out either at a fixed wavelength or by stopping the chromatographic flow, using a CD spectrum between 220 and 420 nm. The method presented is proposed as a supplementary analytical tool in organic stereochemistry.

Links

MSM 143100011, plan (intention)

Name: Struktura a vazebné poměry, vlastnosti a analýza syntetických a přírodních molekulových ansamblů

Investor: Ministry of Education, Youth and Sports of the CR, Structure and character of bonding, properties and analysis of synthetic and natural molecular ensembles

OC D10.20, research and development project

Name: Mikrovlnami aktivované chemické přeměny

Investor: Ministry of Education, Youth and Sports of the CR, Chemical transformations activated by microwaves

Citovat

POSPÍŠIL, Jiří, Martin TRÁVNÍČEK, Albrecht MANNSCHRECK and Milan POTÁČEK. HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions. Chemické Listy. Praha: Česká společnost chemická, 2003, 97/2003, No 12, p. 1993-1197, 5 pp. ISSN 0009-2770.

@article{492665,
   author = {Pospíšil, Jiří and Trávníček, Martin and Mannschreck, Albrecht and Potáček, Milan},
   article_location = {Praha},
   article_number = {12},
   keywords = {HPLC; chiral nonracemic sorbents; circular dichroism detection; stereoisomers; 1;3-dipolar cycloaddition},
   language = {eng},
   issn = {0009-2770},
   journal = {Chemické Listy},
   title = {HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions.},
   volume = {97/2003},
   year = {2003}
}

TY  - JOUR
ID  - 492665
AU  - Pospíšil, Jiří - Trávníček, Martin - Mannschreck, Albrecht - Potáček, Milan
PY  - 2003
TI  - HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions.
JF  - Chemické Listy
VL  - 97/2003
IS  - 12
SP  - 1993-1197
EP  - 1993-1197
PB  - Česká společnost chemická
SN  - 00092770
KW  - HPLC
KW  - chiral nonracemic sorbents
KW  - circular dichroism detection
KW  - stereoisomers
KW  - 1;3-dipolar cycloaddition
N2  - The stereoisomers of several 1,3-dipolar cycloadducts were analysed without previous preparative separation, by HPLC on chiral nonracemic sorbents. This technique contributed significantly to the chemical purity checking, to the determination of the number of stereoisomers present, to the measurement of their relative proportions and to their characterization by retention factors and the circular dichroism (CD) properties. The detection with a CD instrument, in addition to a usual UV photometer, was carried out either at a fixed wavelength or by stopping the chromatographic flow, using a CD spectrum between 220 and 420 nm. The method presented is proposed as a supplementary analytical tool in organic stereochemistry.
ER  -

POSPÍŠIL, Jiří, Martin TRÁVNÍČEK, Albrecht MANNSCHRECK and Milan POTÁČEK. HPLC on chiral nonracemic sorbents with circular dichroism detection: Stereoisomers formed by 1,3-dipolar cycloadditions. \textit{Chemické Listy}. Praha: Česká společnost chemická, 2003, 97/2003, No~12, p.~1993-1197, 5 pp. ISSN~0009-2770.

Detailed Information on Publication Record