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@inproceedings{493081,
author = {Trantírek, Lukáš and Caha, Erik and Fiala, Radovan},
address = {Prague},
booktitle = {Materials Structure},
edition = {1.},
keywords = {RNA; dynamics; NMR; spectroscopy; relaxation; molecular dynamics},
language = {eng},
location = {Prague},
isbn = {1211-5894},
pages = {40-41},
publisher = {Czech and Slovak Crystalographic Association},
title = {NMR Relaxation Studies of Fast Internal Motions in Nucleic Acids},
year = {2003}
}
TY - JOUR
ID - 493081
AU - Trantírek, Lukáš - Caha, Erik - Fiala, Radovan
PY - 2003
TI - NMR Relaxation Studies of Fast Internal Motions in Nucleic Acids
PB - Czech and Slovak Crystalographic Association
CY - Prague
SN - 12115894
KW - RNA
KW - dynamics
KW - NMR
KW - spectroscopy
KW - relaxation
KW - molecular dynamics
N2 - Internal motions of two 14-nt RNA hairpins containing UUCG and GCAA tetraloops were studied by C-13 NMR relaxation and molecular dynamics. While both tetraloops exhibit an increased mobility on the fast time scale, with the GCAA loop we have detected a significant contribution of conformational dynamics on the millisecond to microsecond time scale. This is consistent with the observation that the GNRA family of tetraloops appears more flexible and tolerant of the conformational changes important for molecular recognition.
ER -
TRANTÍREK, Lukáš, Erik CAHA a Radovan FIALA. NMR Relaxation Studies of Fast Internal Motions in Nucleic Acids. In \textit{Materials Structure}. 1. vyd. Prague: Czech and Slovak Crystalographic Association, 2003, s.~40-41. ISBN~1211-5894.
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