LANDA, Leoš, Karel ŠLAIS, Alexandra ŠULCOVÁ a Mariana HANESOVÁ. Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice. Psychiatrie. Praha: Tigis, 2004, roč. 8, Suppl. 4, s. 31-31. ISSN 1211-7579.
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Základní údaje
Originální název Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice
Název anglicky Memantine influence on sensitization to methamphetamine effects on locomotor/exploratory behaviour in mice
Autoři LANDA, Leoš (203 Česká republika, garant), Karel ŠLAIS (203 Česká republika), Alexandra ŠULCOVÁ (203 Česká republika) a Mariana HANESOVÁ (703 Slovensko).
Vydání Psychiatrie, Praha, Tigis, 2004, 1211-7579.
Další údaje
Originální jazyk čeština
Typ výsledku Článek v odborném periodiku
Obor 30104 Pharmacology and pharmacy
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14110/04:00010276
Organizační jednotka Lékařská fakulta
Klíčová slova anglicky behavioural sensitization; methamphetamine; memantine; open field test; mice
Štítky behavioural sensitization, Memantine, methamphetamine, mice, open field test
Změnil Změnil: doc. Mgr. MVDr. Leoš Landa, Ph.D., učo 70449. Změněno: 13. 9. 2004 13:01.
Anotace
Methamphetamine (MET) similarly to other psychostimulant drugs invokes during its repeated administration a significant increase in behavioural responses. This phenomenon is termed behavioural sensitization. There are various reports on involvement of N-methyl-D-aspartate (NMDA) receptor activity in the development and expression of behavioural sensitization, although results of them are rather controversial. Thus, the present study was designed to investigate a possible influence of NMDA receptor non-competitive antagonist memantine (MEM) on sensitization to methamphetamine effects on mouse locomotor/exploratory behaviour in the open field test.
Anotace anglicky
Methamphetamine (MET) similarly to other psychostimulant drugs invokes during its repeated administration a significant increase in behavioural responses. This phenomenon is termed behavioural sensitization. There are various reports on involvement of N-methyl-D-aspartate (NMDA) receptor activity in the development and expression of behavioural sensitization, although results of them are rather controversial. Thus, the present study was designed to investigate a possible influence of NMDA receptor non-competitive antagonist memantine (MEM) on sensitization to methamphetamine effects on mouse locomotor/exploratory behaviour in the open field test.
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