IZAKOVIČOVÁ HOLLÁ, Lydie, Antonín FASSMANN, Anna VAŠKŮ, Monika PÁVKOVÁ GOLDBERGOVÁ, Michal BERÁNEK, Vladimír ZNOJIL, Jiří VANĚK and Jiří VÁCHA. Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis. J Periodontol. Chicago: American Academy of Periodontology, 2005, vol. 76, No 7, p. 15-19. ISSN 0022-3492.
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Basic information
Original name Genetic variations in the human gelatinase A (MMP-2) promoter are not associated with susceptibility to, and severity of, chronic periodontitis
Name in Czech Genetické varianty v promotoru genu pro lidskou gelatinázu (MMP-2) nejsou asociovány s náchylností ke vzniku chronické parodontitidy ani její závažností
Authors IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor), Antonín FASSMANN (203 Czech Republic), Anna VAŠKŮ (203 Czech Republic), Monika PÁVKOVÁ GOLDBERGOVÁ (203 Czech Republic), Michal BERÁNEK (203 Czech Republic), Vladimír ZNOJIL (203 Czech Republic), Jiří VANĚK (203 Czech Republic) and Jiří VÁCHA (203 Czech Republic).
Edition J Periodontol, Chicago, American Academy of Periodontology, 2005, 0022-3492.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30200 3.2 Clinical medicine
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.784
RIV identification code RIV/00216224:14110/05:00013560
Organization unit Faculty of Medicine
UT WoS 000230774200002
Keywords in English gelatinase A; MMP-2; gene; polymorphism; haplotype; periodontitis
Tags gelatinase A, gene, haplotype, MMP-2, periodontitis, polymorphism
Changed by Changed by: prof. MUDr. Lydie Izakovičová Hollá, Ph.D., učo 734. Changed: 17/6/2009 11:47.
Abstract
Gelatinase A (matrix metalloproteinase-2, MMP-2) has been shown to play an important role in the pathogenesis of several disorders, including periodontal diseases. In this study, we test the hypothesis that variations in this gene influence the development and severity of chronic periodontitis.
Abstract (in Czech)
Gelatináza A (matrix metaloproteináza 2, MMP-2) hraje důležitou úlohu v patogeneze některých nemocí, včetně onemocnění parodontu. V této práci jsme testovali hypotézu, že varianty v tomto genu ovlivňují rozvoj a závažnost chronické parodontitidy.
Links
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
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