Safety and tolerability of second and third generation antipsychotic

ČEŠKOVÁ, Eva, Tomáš NOVOTNÝ, A. FLORIÁNOVÁ, Vítězslav PÁLENSKÝ, Radovan PŘIKRYL a J. TOMANOVÁ. Safety and tolerability of second and third generation antipsychotic. Psychiatrie, časopis pro moderní psychiatrii. Praha: Tigis, 2004, roč. 8, Suppl.4, s. 16. ISSN 1211-7579.

Základní údaje

Originální název

Safety and tolerability of second and third generation antipsychotic

Název anglicky

Safety and tolerability of second and third gneration antipsychotic

Autoři

ČEŠKOVÁ, Eva (203 Česká republika, garant), Tomáš NOVOTNÝ (203 Česká republika), A. FLORIÁNOVÁ (203 Česká republika), Vítězslav PÁLENSKÝ (203 Česká republika), Radovan PŘIKRYL (203 Česká republika) a J. TOMANOVÁ (203 Česká republika)

Vydání

Psychiatrie, časopis pro moderní psychiatrii, Praha, Tigis, 2004, 1211-7579

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Další údaje

Jazyk

čeština

Typ výsledku

Článek v odborném periodiku

Obor

30000 3. Medical and Health Sciences

Stát vydavatele

Česká republika

Utajení

není předmětem státního či obchodního tajemství

Kód RIV

RIV/00216224:14110/04:00021295

Organizační jednotka

Lékařská fakulta

Klíčová slova anglicky

safety and tolerability; antipsychotics; QT interval

Štítky

antipsychotics, QT interval, safety and tolerability

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Anotace

V originále

Prolongation of the QT interval is of concern since the pacients may be at risk for TdP, a serious ventricular arrythmia.In hospitalised psychiatric patients a 12-lead ECG was recorded, the QT interval was measured manually, the Bazett formula was used for correction. The total number of 375 ECG records was obtained. In 11 of 375 records(i.e.2,9%) the borderline or pathologics valuesof QT interval were found. The occurrence of abnormal QTc was lower than in so-far avilable literature. This could be connected with the change of spectrum of antipsychotics used, the general trend to lower doses of antipsychotics.

Anglicky

Prolongation of the QT interval is of concern since the pacients may be at risk for TdP, a serious ventricular arrythmia.In hospitalised psychiatric patients a 12-lead ECG was recorded, the QT interval was measured manually, the Bazett formula was used for correction. The total number of 375 ECG records was obtained. In 11 of 375 records(i.e.2,9%) the borderline or pathologics valuesof QT interval were found. The occurrence of abnormal QTc was lower than in so-far avilable literature. This could be connected with the change of spectrum of antipsychotics used, the general trend to lower doses of antipsychotics.