IZAKOVIČOVÁ HOLLÁ, Lydie. Editorial: Regulation of pathogenetic aspects of allergic diseases. Current Drug Targets - Inflammation and Allergy. Bentham Science Publishers, 2005, vol. 4, No 2, p. 139-140. ISSN 1568-010X.
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Basic information
Original name Editorial: Regulation of pathogenetic aspects of allergic diseases
Name in Czech Předmluva: Regulace patogenetických aspektů alergických nemocí
Authors IZAKOVIČOVÁ HOLLÁ, Lydie (203 Czech Republic, guarantor).
Edition Current Drug Targets - Inflammation and Allergy, Bentham Science Publishers, 2005, 1568-010X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30102 Immunology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/05:00013585
Organization unit Faculty of Medicine
Keywords in English allergic diseases; pathogenetic aspect; cytokine network; nitric oxide; CD14
Tags allergic diseases, CD14, cytokine network, nitric oxide, pathogenetic aspect
Changed by Changed by: prof. MUDr. Lydie Izakovičová Hollá, Ph.D., učo 734. Changed: 20/6/2009 21:04.
Abstract
This special issue of Current Drug Targets Inflammation and Allergy entitled Regulation of pathogenetic aspects of allergic diseases is focused on the key areas of the regulation of pathogenetic aspects of allergic diseases including imbalanced Th1/Th2 responses with alterations of the cytokine network, functions of beta2-receptors, CD14 and Toll-like receptors and their alteration with responsiveness to therapeutic agents, altered prostaglandin and nitric oxide metabolisms and remodeling extracellular matrix by enzymes from matrix metalloproteinase family. This issue covers description of the structure of these substances and their genes, as well as methods for their study, results of genetic studies with the identification of the molecular targets and the relationship of this target to the allergic disorders.
Abstract (in Czech)
Toto speciální číslo Current Drug Targets - Inflammation and Allergy nazvané "Regulace patogenetických aspektů alergických nemocí" je zaměřeno na klíčové oblasti regulace patogenetických aspektů alergických chorob - imbalanci Th1/Th2 odpovědi s alterací cytokinové sítě, funkci beta2-receptorů, CD14 a Toll-like receptorů a jejich změny ve vztahu k odpovídavosti na léčbu, změny prostaglandinů a metabolizmu oxidu dusnatého a remodelaci mezibuněčné hmoty enzymy z rodiny matrix metaloproteináz. Toto číslo se zabývá popisem struktury těchto látek a jejich genů, jakož i metodami pro jejich studium, výsledky genetických prací s nalezením molekulárních cílů a jejich spojení s alergickými chorobami.
Links
MSM 141100002, plan (intention)Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases
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