SMILEK, Pavel, Rom KOSTŘICA, Jan ROTTENBERG, Karel VESELÝ a Ladislav DUŠEK. PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS. In Sborník abstrakt a program 68. kongresu České spol. pro otorinolaryngologii a chir. hlavy a krku. Brno: Medica Publishing and consulting s.r.o., 2005, s. 111. ISBN 80-239-5112-2.
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Základní údaje
Originální název PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS
Název česky Prediktivní parametry karcinomu faryngu a supraglottis
Název anglicky PREDICTIVE PARAMETERS OF THE PHARYNX AND SUPRAGLOTTIC CARCINOMAS
Autoři SMILEK, Pavel, Rom KOSTŘICA, Jan ROTTENBERG, Karel VESELÝ a Ladislav DUŠEK.
Vydání Brno, Sborník abstrakt a program 68. kongresu České spol. pro otorinolaryngologii a chir. hlavy a krku, s. 111-111, 2005.
Nakladatel Medica Publishing and consulting s.r.o.
Další údaje
Originální jazyk čeština
Typ výsledku Stať ve sborníku
Obor 30200 3.2 Clinical medicine
Stát vydavatele Česká republika
Utajení není předmětem státního či obchodního tajemství
Organizační jednotka Lékařská fakulta
ISBN 80-239-5112-2
Klíčová slova anglicky head and neck cancer; prognosis; p53; DNA flow-cytometry
Štítky DNA flow-cytometry, head and neck cancer, p53, prognosis
Změnil Změnil: doc. MUDr. Pavel Smilek, Ph.D., učo 1801. Změněno: 22. 6. 2005 08:16.
Anotace
The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis. Besides routine examinations, flow cytometric analysis of was performed, p53 and Ki-67 markers were established by means of immunohistochemistry. Furthermore mitotic and apoptotic index were established. Cytokinetic parameters and proliferation activity were found as important predictors of the second level (after recognizing stage, grade and DNA status of the tumor). Early progressed cases have typically decreased SPF fraction combined with increased mitotic activity.
Anotace anglicky
The analysis was carried out with a set of 60 patients suffering from carcinoma of the pharynx and supraglottis. Besides routine examinations, flow cytometric analysis of was performed, p53 and Ki-67 markers were established by means of immunohistochemistry. Furthermore mitotic and apoptotic index were established. Cytokinetic parameters and proliferation activity were found as important predictors of the second level (after recognizing stage, grade and DNA status of the tumor). Early progressed cases have typically decreased SPF fraction combined with increased mitotic activity.
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