Age related changes of baroreflex sensitivity in children and adolescents
ZÁVODNÁ, Eva, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Bohumil FIŠER a Nataša HONZÍKOVÁ. Age related changes of baroreflex sensitivity in children and adolescents. In 14th Meeting of Paediatric Research of Cenral European Countries. 2005. |
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Základní údaje | |
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Originální název | Age related changes of baroreflex sensitivity in children and adolescents |
Název česky | Na věku závislé změny baroreflexní citlivosti u dětí a dospívajících |
Název anglicky | Age related changes of baroreflex sensitivity in children and adolescents |
Autoři | ZÁVODNÁ, Eva (203 Česká republika, garant), Hana HRSTKOVÁ (203 Česká republika), Zuzana NOVÁKOVÁ (203 Česká republika), Bohumil FIŠER (203 Česká republika) a Nataša HONZÍKOVÁ (203 Česká republika). |
Vydání | 14th Meeting of Paediatric Research of Cenral European Countries, 2005. |
Další údaje | |
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Originální jazyk | čeština |
Typ výsledku | Konferenční abstrakt |
Obor | 30105 Physiology |
Stát vydavatele | Česká republika |
Utajení | není předmětem státního či obchodního tajemství |
Kód RIV | RIV/00216224:14110/05:00013798 |
Organizační jednotka | Lékařská fakulta |
Klíčová slova anglicky | baroreflex sensitivity; developemnt; children; adolescents |
Štítky | Adolescents, baroreflex sensitivity, children, developemnt |
Změnil | Změnila: MUDr. Bc. Eva Závodná, Ph.D., učo 19752. Změněno: 1. 4. 2010 17:24. |
Anotace |
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The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age. |
Anotace anglicky |
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The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age. |
Návaznosti | |
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MSM0021622402, záměr | Název: Časná diagnostika a léčba kardiovaskulárních chorob |
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, Časná diagnostika a léčba kardiovaskulárních chorob | |
NR8006, projekt VaV | Název: Autonomní oběhové funkce, funkce myokardu a kardiorespirační funkce u dětí a adolescentů po léčbě zhoubného nádoru |
Investor: Ministerstvo zdravotnictví ČR, Autonomní oběhové funkce, funkce myokardu a kardiorespirační funkce u dětí a adolescentů po léčbě zhoubného nádoru |
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